3-Fluoro-4-methoxyaniline
Synonym(s):3-Fluoro-4-methoxyaniline
- CAS NO.：366-99-4
- Empirical Formula: C7H8FNO
- Molecular Weight: 141.14
- MDL number: MFCD00075040
- EINECS: 627-615-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:19:41
What is 3-Fluoro-4-methoxyaniline?
Chemical properties
light beige to yellow-brown crystalline powder
The Uses of 3-Fluoro-4-methoxyaniline
3-Fluoro-4-methoxyaniline was used as a reagent in the synthesis of novel leucine ureido derivatives which have potent inhibitory activity againt aminopeptidase N. Also used in the synthesis of novel mGluR1 antagonists for the treatment of chronic pain.
General Description
Arrhenius parameter has been measured for the reactions of 3-fluoro-p-anisidine (3-fluoro-4-methoxyaniline) with picryl chloride.
Properties of 3-Fluoro-4-methoxyaniline
| Melting point: | 81-83 °C (lit.) |
| Boiling point: | 135 °C/18 mmHg (lit.) |
| Density | 1.1382 (estimate) |
| Flash point: | >110°C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 4.18±0.10(Predicted) |
| color | Light beige to yellow-brown |
| BRN | 2717083 |
| CAS DataBase Reference | 366-99-4(CAS DataBase Reference) |
Safety information for 3-Fluoro-4-methoxyaniline
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Fluoro-4-methoxyaniline
3-Fluoro-4-methoxyaniline manufacturer
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product: 3-Fluoro-4-methoxy aniline 366-99-4 98%
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