3-ETHYL-3-METHYLGLUTARIMIDE

Chemical properties

white to off-white flakes or powder

The Uses of 3-ETHYL-3-METHYLGLUTARIMIDE

CNS stimulant;GABA antagonist

Definition

ChEBI: 4-ethyl-4-methylpiperidine-2,6-dione is a member of piperidones.

brand name

Megimide (Abbott).

General Description

White crystalline solid. Sublimes at 212°F and 200 mm pressure.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

3-ETHYL-3-METHYLGLUTARIMIDE is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition it emits toxic fumes.

Fire Hazard

Flash point data for 3-ETHYL-3-METHYLGLUTARIMIDE are not available. 3-ETHYL-3-METHYLGLUTARIMIDE is probably not flammable.

Safety Profile

Poison by ingestion, intravenous, intraperitoneal, intramuscular, subcutaneous, and parented routes. Human systemic effects by ingestion: wakefulness, hallucinations, distorted perceptions, toxic psychosis. An analeptic, central nervous system stimulant; used to counteract barbiturate poisoning. When heated to decomposition it emits toxic fumes of NOx.