3-Chloro-2,5-difluoropyridine
- CAS NO.：851179-00-5
- Empirical Formula: C5H2ClF2N
- Molecular Weight: 149.53
- MDL number: MFCD09998887
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-04 16:04:00
What is 3-Chloro-2,5-difluoropyridine?
The Uses of 3-Chloro-2,5-difluoropyridine
3-Chloro-2,5-difluoropyridine is an intermediate used to prepare selective protein kinase C θ (PKCθ) inhibitors for the treatment of autoimmune diseases.
Properties of 3-Chloro-2,5-difluoropyridine
| Melting point: | 10-12℃ |
| Boiling point: | 136-137℃ |
| Density | 1.451±0.06 g/cm3(Predicted) |
| refractive index | 1.4786 (589.3 nm 20℃) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform, Ethyl Acetate |
| pka | -5.14±0.20(Predicted) |
| form | Oil |
| color | Clear Colorless |
Safety information for 3-Chloro-2,5-difluoropyridine
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H302:Acute toxicity,oral H312:Acute toxicity,dermal H314:Skin corrosion/irritation H318:Serious eye damage/eye irritation H332:Acute toxicity,inhalation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Chloro-2,5-difluoropyridine
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