3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
Synonym(s):4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid;C 75;C-75
- CAS NO.：218137-86-1
- Empirical Formula: C14H22O4
- Molecular Weight: 254.32
- MDL number: MFCD03265452
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-06-03 22:32:03
What is 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE?
The Uses of 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
C75 has been used:
- as a fatty acid synthase (FASN) inhibitor to test its ability in the direct inhibition of FASN to attenuate mammosphere formation as compared to metformin
- as a pharmacological inhibitor to inhibit fatty acid synthesis in glioma stem cells (GSCs)
- as FAS inhibitor in the pre-treatment of Chang cells to inhibit lipogenesis and reverse the senescence induced by hydrogen peroxide
Definition
ChEBI: 4-methylene-2-octyl-5-oxo-3-oxolanecarboxylic acid is a gamma-lactone.
Biochem/physiol Actions
C75 helps to increase the cancer‐killing capability of ionizing radiation.
Properties of 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
| Boiling point: | 432.1±45.0 °C(Predicted) |
| Density | 1.08±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: 18 mg/mL |
| form | solid |
| pka | 3.08±0.40(Predicted) |
| color | off-white |
Safety information for 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
New Products
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