3-Bromo-1,1,1-trifluoroacetone
- CAS NO.：431-35-6
- Empirical Formula: C3H2BrF3O
- Molecular Weight: 190.95
- MDL number: MFCD00039237
- EINECS: 207-071-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:19:36
What is 3-Bromo-1,1,1-trifluoroacetone ?
Chemical properties
clear colorless to yellowish liquid
The Uses of 3-Bromo-1,1,1-trifluoroacetone
3-Bromo-1,1,1-trifluoroacetone may be used in the synthesis of:
- 3-nonylthio-1,1,1-trifluoropropan-2-one
- cyclic tetrapeptides containing trifluoromethyl and pentafluoroethyl ketone as zinc binding functional group
- perfluoroalkylated trans-allylic alcohols
The Uses of 3-Bromo-1,1,1-trifluoroacetone
1-Bromo-3,3,3-trifluoroacetone is used in the preparation of 3-nonylthio-1,1,1-trifluoropropan-2-one and perfluoroalkylated trans-allylic alcohols. It is involved in the synthesis of cyclic tetrapeptides. Further, it reacts with potassium enolate of ethyl 4,4,4-trifluoroacetoacetate to produce ethyl 2,4-bis(trifluoromethyl)-4-hydroxydihydro-3-furoate.
General Description
3-Bromo-1,1,1-trifluoroacetone reacts with potassium enolate of ethyl 4,4,4-trifluoroacetoacetate to yield ethyl 2,4-bis(trifluoromethyl)-4-hydroxydihydro-3-furoate.
Properties of 3-Bromo-1,1,1-trifluoroacetone
| Melting point: | <-80°C |
| Boiling point: | 87 °C/743 mmHg (lit.) |
| Density | 1.839 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 41 °F |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| form | Liquid |
| color | Clear colorless to yellow |
| Specific Gravity | 1.839 |
| Water Solubility | Immiscible with water. |
| Sensitive | Lachrymatory |
| BRN | 1703387 |
| CAS DataBase Reference | 431-35-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-Bromo-3,3,3-trifluoroacetone(431-35-6) |
Safety information for 3-Bromo-1,1,1-trifluoroacetone
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H225:Flammable liquids H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Bromo-1,1,1-trifluoroacetone
| InChIKey | ONZQYZKCUHFORE-UHFFFAOYSA-N |
New Products
Methyl N-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-N-nitroso-L-valinate Levofloxacin - Impurity B/ Levofloxacin Related Compound A Ivabradine R isomer Escitalopram - Impurity K Escitalopram Cyno dilol Impurity Paroxetine EP impurity I/Paroxetine Anhydrous EP Impurity I 2-Amino-5-Bromo-6-Chloropyridine 3-Amino-5-bromopicolinic acid 1-(7,8-Dinitro-4,5-dihydro-1H-1,5-methanobenzo[d]azepin-3(2H)-yl)-2,2,2-trifluoroethanone 2-Amino-3-Bromo-5-Cyanopyridine 2-Amino-3-Chloropyridine 2,5-Dibromo-3-MethylpyridineRelated products of tetrahydrofuran
You may like
-
431-65-6 3-Bromo-1,1,1-trifluoroacetone 98%View Details
431-65-6 -
1-Bromo-3,3,3-trifluoroacetone CAS 431-35-6View Details
431-35-6 -
3-Bromo-1,1,1-trifluoroacetone CAS 431-35-6View Details
431-35-6 -
17471-10-2 Diphenhydramine EP impurity-A /Diphenhydramine Related Compound A NLT 95%View Details
17471-10-2 -
Dorzolamide Related Compound B/Dorzolamide EP Impurity B NLT 95%View Details
120279-90-5 -
76824-16-3 Famotidine - Impurity D NLT 95%View Details
76824-16-3 -
118-23-0 NLT 95%View Details
118-23-0 -
573704-41-3 NLT 95%View Details
573704-41-3
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.