3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE
Synonym(s):3-((5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methyl)pyridine hydrochloride, P2X7 Purinergic Receptor Antagonist, A 438079, A438079, A-438079;A 438079 - CAS 899507-36-9 - Calbiochem
- CAS NO.：899507-36-9
- Empirical Formula: C13H9Cl2N5
- Molecular Weight: 306.15
- MDL number: MFCD09971142
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-03 09:04:23
![3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE Structural](https://img.chemicalbook.in/CAS/GIF/899507-36-9.gif)
What is 3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE?
The Uses of 3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE
3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine is a 1-Benzyl-5-aryltetrazole derivative and potential antagonists for the P2X7 receptor.
What are the applications of Application
A 438079 hydrochloride is a competitive P2X7 receptor antagonist that is inactive at other P2 receptors
Biological Activity
Competitive P2X 7 receptor antagonist (pIC 50 = 6.9 for the inhibition of Ca 2+ influx in the human recombinant P2X 7 cell line). Devoid of activity at other P2 receptors (IC 50 >> 10 μ M). Possesses antinociceptive activity in models of neuropathic pain in vivo .
Properties of 3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE
| storage temp. | Desiccate at RT |
| solubility | Soluble in DMSO |
| form | Powder |
| color | White to off-white |
Safety information for 3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE
Computed Descriptors for 3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE
3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE manufacturer
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product: 3-((5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl)methyl)pyridine 95.00%
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