2,5-Difluorobenzyl bromide
Synonym(s):α-Bromo-2,5-difluorotoluene
- CAS NO.：85117-99-3
- Empirical Formula: C7H5BrF2
- Molecular Weight: 207.02
- MDL number: MFCD00009897
- EINECS: 285-651-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:14:21
What is 2,5-Difluorobenzyl bromide?
Chemical properties
CLEAR YELLOW LIQUID
The Uses of 2,5-Difluorobenzyl bromide
2,5-Difluorobenzyl bromide has been used in the synthesis of:
- novel series of 4-aryl, 4-phenylsulfonyl cyclohexananone-derived γ-secretase inhibitors, for the potential treatment of Alzheimer′s disease
- sulfonamide, amide and acyclic amine derivatives
Properties of 2,5-Difluorobenzyl bromide
| Boiling point: | 28 °C |
| Density | 1.609 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 60 °F |
| storage temp. | Inert atmosphere,2-8°C |
| form | clear liquid |
| color | Colorless to Light orange to Yellow |
| Specific Gravity | 1.6090 |
| BRN | 7089248 |
| CAS DataBase Reference | 85117-99-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 2,5-Difluorobenzyl bromide(85117-99-3) |
Safety information for 2,5-Difluorobenzyl bromide
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H225:Flammable liquids H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,5-Difluorobenzyl bromide
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