2,5-Dichlorophenylboronic acid
Synonym(s):2,5-Dichlorobenzeneboronic acid
- CAS NO.:135145-90-3
- Empirical Formula: C6H5BCl2O2
- Molecular Weight: 190.82
- MDL number: MFCD01863182
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 00:29:21
What is 2,5-Dichlorophenylboronic acid?
Chemical properties
White to off-white powder
The Uses of 2,5-Dichlorophenylboronic acid
2,5-Dichlorophenylboronic Acid is a reactant in the synthesis of Dipeptidyl peptidase IV (DPP4) inhibitors for the treatment of type 2 diabetes.
The Uses of 2,5-Dichlorophenylboronic acid
Reactant for:• ;Regioselective iodination using silver salts1• ;Pd-catalyzed Suzuki-Miyaura coupling2• ;Rhodium(I)-catalyzed carbonylative cyclization of alkynes3• ;Copper catalyzed coupling reactions4
The Uses of 2,5-Dichlorophenylboronic acid
suzuki reaction
Properties of 2,5-Dichlorophenylboronic acid
| Melting point: | 150 °C(lit.) |
| Boiling point: | 343.6±52.0 °C(Predicted) |
| Density | 1.47±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Acetone (Slightly), Methanol (Slightly) |
| form | Powder |
| pka | 7.26±0.58(Predicted) |
| color | White to off-white |
| BRN | 4801290 |
| CAS DataBase Reference | 135145-90-3(CAS DataBase Reference) |
Safety information for 2,5-Dichlorophenylboronic acid
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2,5-Dichlorophenylboronic acid
| InChIKey | NNTFPBXQPOQRBT-UHFFFAOYSA-N |
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