2,4,6-Trifluoroaniline

CAS NO.：363-81-5
Empirical Formula: C6H4F3N
Molecular Weight: 147.1
MDL number: MFCD00007650
EINECS: 206-660-8
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:21:00

What is 2,4,6-Trifluoroaniline?

Chemical properties

COLORLESS TO LIGHT GREY CRYSTALS

The Uses of 2,4,6-Trifluoroaniline

2,4,6-Trifluoroaniline was used in the synthesis of 3-nitro-2,4,6 -trifluoroacetanilide; eries of N?-phenyl-N-(1- phenyl cyclopentyl)-methyl ureas and 4-substituted 2,6-difluoro N-aryl pyridinones.

The Uses of 2,4,6-Trifluoroaniline

2,4,6-Trifluoroaniline was used in the synthesis of:

3-nitro-2,4,6 -trifluoroacetanilide
series of N′-phenyl-N-(1- phenyl cyclopentyl)-methyl ureas
4-substituted 2,6-difluoro N-aryl pyridinones

Properties of 2,4,6-Trifluoroaniline

Melting point:	33-37 °C (lit.)
Boiling point:	57 °C/22 mmHg (lit.)
Density	1.3510 (estimate)
Flash point:	136 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to lump to clear liquid
pka	1.87±0.10(Predicted)
color	White or Colorless to Light yellow
Water Solubility	Insoluble in water.
BRN	2831022
CAS DataBase Reference	363-81-5(CAS DataBase Reference)
NIST Chemistry Reference	2,4,6-Trifluoroaniline(363-81-5)

Safety information for 2,4,6-Trifluoroaniline

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H228:Flammable solids H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P240:Ground/bond container and receiving equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.