2,4-Dimethyl-3-pentanone

Chemical properties

2,4-Dimethyl-3-pentanone is a colorless liquid with a characteristic odor similar to that of camphor; it is insoluble in water but soluble in organic solvents.

The Uses of 2,4-Dimethyl-3-pentanone

DiPK has been used in automotive assembly plants as a ketonic solvent for fuel injectors and as a photoinitiator for IV-curable acrylic coatings in optical fiber gratings. The U.S. production ofDnPK was estimated to be,500,000 lb in 2005 according to the 2006 U.S. EPA Inventory Update Reporting database.

The Uses of 2,4-Dimethyl-3-pentanone

2,4-Dimethyl-3-pentanone was used in an experimental method to measure the equilibrium isotopic fractionation factor (α_eq ) for C-bound H positions adjacent to carbonyl group in ketones.

The Uses of 2,4-Dimethyl-3-pentanone

2,4-Dimethyl-3-pentanone is used in an experimental method to measure the equilibrium isotopic fractionation factor (αeq ) for C-bound H positions adjacent to carbonyl group in ketones.It is a carbonyl compound used in an experimental method to measure the equilibrium isotopic fractionation factor (αeq ) for C-bound H positions adjacent to carbonyl group in ketones. Isobutyrone is a very useful synthetic intermediate. It is an intermediate used to prepare α-aryl ketones. It is also used in Grignard reactions.

Production Methods

2,4-Dimethyl-3-pentanone is preferably obtained by ketonization of isobutyric acid over a thorium oxide or zirconium oxide catalyst at 430℃.

Definition

ChEBI: 2,4-dimethyl-3-pentanone is a pentanone that is pentan-3-one substituted by methyl groups at positions 2 and 4 respectively. It has a role as a metabolite. It is functionally related to a pentan-3-one.

Synthesis Reference(s)

Tetrahedron Letters, 24, p. 4207, 1983 DOI: 10.1016/S0040-4039(00)88301-X

Purification Methods

Dry the ketone with CaSO4, shake it with chromatographic alumina and fractionally distil it from P2O5 under N2. [Beilstein 1 IV 3334.]