2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine

CAS NO.：927871-76-9
Empirical Formula: C11H15NOS
Molecular Weight: 209.31
MDL number: MFCD12546447
SAFETY DATA SHEET (SDS)
Update Date: 2026-07-17 09:03:53

What is 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine?

The Uses of 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine

It is a benzothiazepine derivative that binds the RyR1 channel and enhances the binding affinity of Calstabin-1. By preventing the depletion of Calstabin-1 from the RyR1 complex, S 107 slows muscle fatique and reduces muscle damage in exercised mice. In a murine model of Duchenne muscular dystrophy, S 107 reduces biochemical and histological evidence of the muscle damage associated with muscular dystrophy, improves muscle function, and increases exercise performance.

Properties of 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine

Boiling point:	318.8±42.0 °C(Predicted)
Density	1?+-.0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	7.74±0.20(Predicted)
form	neat
form	Solid
color	White to off-white
Water Solubility	Water : ≥ 132 mg/mL (537.09 mM)
BRN	18342799

Safety information for 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine

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