2,3-Epoxypropyltrimethylammonium chloride

Synonym(s):(2,3-Epoxypropyl)trimethylammonium chloride

CAS NO.：3033-77-0
Empirical Formula: C6H14ClNO
Molecular Weight: 151.63
MDL number: MFCD00011940
EINECS: 221-221-0
SAFETY DATA SHEET (SDS)
Update Date: 2026-06-05 18:44:30

2,3-Epoxypropyltrimethylammonium chloride Structural

What is 2,3-Epoxypropyltrimethylammonium chloride?

Description

Used in the production of cationic starch for the paper industry, 2,3-Epoxypropyl trimethyl ammonium chloride (EPTMAC) caused contact dermatitis in the workers.

Chemical properties

solid

The Uses of 2,3-Epoxypropyltrimethylammonium chloride

Reagent used for synthesis and antimicrobial activity of a water soluble chitosan derivative with a fiber-reactive group.

The Uses of 2,3-Epoxypropyltrimethylammonium chloride

Glycidyltrimethylammonium chloride be used as a derivatizing agent to synthesize N-(2-hydroxypropyl)-3-trimethylammonium chitosan chloride (HTCC), a water-soluble chitosan derivative, by reacting with chitosan. HTCC can form nanocomposite films with silver nanoparticles that show good antimicrobial property and optical transparency. Cationic starches can also be prepared by derivatization of starch with GTMAC.

General Description

Glycidyltrimethylammonium chloride (GTMAC) is a cationizing agent commonly used for starch modification.

Contact allergens

Used in the production of cationic starch for the paper industry; EPTMAC caused contact dermatitis in workers.

Safety Profile

Suspected carcinogen. Poison by subcutaneous route. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl-, NH3, and NOx. See also AMMONIUM CHLORIDE.

Properties of 2,3-Epoxypropyltrimethylammonium chloride

Melting point:	137-139 °C
Density	1.13 g/mL at 20 °C(lit.)
refractive index	1.48
Flash point:	170 °C
storage temp.	2-8°C
solubility	Methanol (Slightly), Water (Sparingly)
form	Oil
color	Colourless
Water Solubility	852g/L at 20℃
BRN	3914931
Stability:	Stable. Incompatible with oxidizing agents
CAS DataBase Reference	3033-77-0(CAS DataBase Reference)
EPA Substance Registry System	Glycidyltrimethylammonium chloride (3033-77-0)

Safety information for 2,3-Epoxypropyltrimethylammonium chloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H341:Germ cell mutagenicity H350:Carcinogenicity H373:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P201:Obtain special instructions before use. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention.