2,2',4'-Trichloroacetophenone
Synonym(s):ω,2,4-Trichloroacetophenone;2,4-Dichlorophenacyl chloride
- CAS NO.：4252-78-2
- Empirical Formula: C8H5Cl3O
- Molecular Weight: 223.48
- MDL number: MFCD00000934
- EINECS: 224-218-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:27:06
What is 2,2',4'-Trichloroacetophenone?
Chemical properties
yellow crystalline powde
The Uses of 2,2',4'-Trichloroacetophenone
α,2,4-Trichloroacetophenone is a reagent used in the synthesis of isoconazole, a potent antifungal agent.
General Description
Off-white crystalline solid.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2,2',4'-Trichloroacetophenone is incompatible with strong oxidizers and strong bases. .
Fire Hazard
2,2',4'-Trichloroacetophenone is probably combustible.
Properties of 2,2',4'-Trichloroacetophenone
| Melting point: | 47-54 °C(lit.) |
| Boiling point: | 130-135 °C4 mm Hg(lit.) |
| Density | 1,312 g/cm3 |
| refractive index | 1.5510 (estimate) |
| Flash point: | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | 60 mg/L (20°C) |
| form | Solid |
| color | beige to yellow |
| PH | 4.96 at 25.1℃ and 10g/L |
| Water Solubility | 60 mg/L (20 ºC) |
| Sensitive | Lachrymatory |
| BRN | 957098 |
| CAS DataBase Reference | 4252-78-2(CAS DataBase Reference) |
| EPA Substance Registry System | Ethanone, 2-chloro-1-(2,4-dichlorophenyl)- (4252-78-2) |
Safety information for 2,2',4'-Trichloroacetophenone
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,2',4'-Trichloroacetophenone
2,2',4'-Trichloroacetophenone manufacturer
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