2,2'-Thiodiethanol
Synonym(s):2,2′-Thiobis(ethanol);Bis(2-hydroxyethyl) sulfide;Thiodiethylene glycol;Thiodiglycol
- CAS NO.：111-48-8
- Empirical Formula: C4H10O2S
- Molecular Weight: 122.19
- MDL number: MFCD00002910
- EINECS: 203-874-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-31 14:38:37
What is 2,2'-Thiodiethanol?
Chemical properties
colourless liquid with characteristic odour.
The Uses of 2,2'-Thiodiethanol
antineoplastic, alkylating agent
Definition
ChEBI: A diol that is pentane-1,5-diol in which the methylene group at position 3 is replaced by a sulfur atom
Hazard
Do not use with hydrochloric acid.
Flammability and Explosibility
Not classified
Properties of 2,2'-Thiodiethanol
| Melting point: | −16 °C(lit.) |
| Boiling point: | 164-166 °C20 mm Hg(lit.) |
| Density | 1.221 g/mL at 25 °C(lit.) |
| vapor pressure | 0.26Pa at 20℃ |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | -20°C |
| solubility | alcohol: miscible(lit.) |
| form | liquid |
| pka | 14.14±0.10(Predicted) |
| Merck | 14,9330 |
| BRN | 1236325 |
| Stability: | Stable. Incompatible with strong oxidizing agents. Reacts with a wide variety of compounds. Flammable. |
| CAS DataBase Reference | 111-48-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Thiodiglycol(111-48-8) |
| EPA Substance Registry System | Ethanol, 2,2'-thiobis- (111-48-8) |
Safety information for 2,2'-Thiodiethanol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 2,2'-Thiodiethanol
New Products
N,O-Dimethylhydroxylamine hydrochloride DL-beta-(3-Bromophenyl)alanine N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid (R)-1-Benzyl-3-pyrrolidinecarbonitrile Bupropian related compound F Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) 1-methyl amino-2,4-dinitro benzene 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy Benzylcyanide 3-Hydroxypropionitrile 4-Bromo BenzylcyanideRelated products of tetrahydrofuran
![Bis[2-(succiniMidooxycarbonyloxy)ethyl] Sulfone](https://img.chemicalbook.in/CAS/GIF/57683-72-4.gif)
![2-[(2-PHENOXYETHYL)THIO]ACETIC ACID](https://img.chemicalbook.in/CAS/GIF/75434-70-7.gif)
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