2,2'-Thiodiethanol
Synonym(s):2,2′-Thiobis(ethanol);Bis(2-hydroxyethyl) sulfide;Thiodiethylene glycol;Thiodiglycol
- CAS NO.:111-48-8
- Empirical Formula: C4H10O2S
- Molecular Weight: 122.19
- MDL number: MFCD00002910
- EINECS: 203-874-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-31 14:38:37
What is 2,2'-Thiodiethanol?
Chemical properties
colourless liquid with characteristic odour.
The Uses of 2,2'-Thiodiethanol
antineoplastic, alkylating agent
Definition
ChEBI: A diol that is pentane-1,5-diol in which the methylene group at position 3 is replaced by a sulfur atom
Hazard
Do not use with hydrochloric acid.
Flammability and Explosibility
Not classified
Properties of 2,2'-Thiodiethanol
| Melting point: | −16 °C(lit.) |
| Boiling point: | 164-166 °C20 mm Hg(lit.) |
| Density | 1.221 g/mL at 25 °C(lit.) |
| vapor pressure | 0.26Pa at 20℃ |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | -20°C |
| solubility | alcohol: miscible(lit.) |
| form | liquid |
| pka | 14.14±0.10(Predicted) |
| Merck | 14,9330 |
| BRN | 1236325 |
| Stability: | Stable. Incompatible with strong oxidizing agents. Reacts with a wide variety of compounds. Flammable. |
| CAS DataBase Reference | 111-48-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Thiodiglycol(111-48-8) |
| EPA Substance Registry System | Ethanol, 2,2'-thiobis- (111-48-8) |
Safety information for 2,2'-Thiodiethanol
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 2,2'-Thiodiethanol
New Products
3-azanyl-3-phenyl-propanoic acid 3-AMINO-3-(2-METHYLPHENYL)PROPANOIC ACID 3-AMINO-3-M-TOLYL-PROPIONIC ACID Nitroso Irbesartan N-Nitroso Nortriptyline 1-nitro-3,5-dimethyl adamantine (NMEM) 3-(2-aminoethyl) benzene sulfonamide Nabumetone Impurity 5 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one 4-dimethylaminopyridine 3-Bromo-2-Methyl-5-Nitropyridine 2-Chloro Isonicotinic acid methyl ester 2-(Ethoxymethylene)propanedinitrile 5-Bromo-3-Methyl-2-Pyridinecarboxylic acid 5-Chloro-pyridine-2-carboxylic acid amideRelated products of tetrahydrofuran
![Bis[2-(succiniMidooxycarbonyloxy)ethyl] Sulfone](https://img.chemicalbook.in/CAS/GIF/57683-72-4.gif)






![2-[(2-PHENOXYETHYL)THIO]ACETIC ACID](https://img.chemicalbook.in/CAS/GIF/75434-70-7.gif)
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