2,2'-DIBROMO-1,1'-BINAPHTHYL

CAS NO.：74866-28-7
Empirical Formula: C20H12Br2
Molecular Weight: 412.12
MDL number: MFCD00188005
EINECS: 626-733-1
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 06:05:08

What is 2,2'-DIBROMO-1,1'-BINAPHTHYL?

The Uses of 2,2'-DIBROMO-1,1'-BINAPHTHYL

The synthesis of this class of compounds relies on the lithiation of racemic 2,2'-dibromo-1,1'-binaphthyl with t-BuLi followed by addition of Ph 2 PCl.

Purification Methods

Purify the binaphthyl by chromatography through a silica gel column (70-230mesh) using hexane as eluent. It gives pale yellow crystals from EtOH with m 187.3-187.9o. The R-(+)-enantiomer [86688-08-6] crystallises from hexane with m 157-157.5o and [] D +32.9o (c 1, pyridine) [Brown et al. J Org Chem 50 4345 1985]. [Okamoto et al. J Am Chem Soc 103 69711981, Beilstein 5 III 2465.]

Properties of 2,2'-DIBROMO-1,1'-BINAPHTHYL

Melting point:	178-183 °C
Boiling point:	178-183°C
Density	1.614±0.06 g/cm3(Predicted)
Flash point:	178-183°C
storage temp.	Sealed in dry,Room Temperature
solubility	soluble in Toluene
form	Powder
color	white to off-white
Water Solubility	Sparingly Soluble in water.
CAS DataBase Reference	74866-28-7(CAS DataBase Reference)

Safety information for 2,2'-DIBROMO-1,1'-BINAPHTHYL

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H413:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment.