2-Thiohydantoin
Synonym(s):2-Thioxo-4-imidazolidinone;NSC 11772
- CAS NO.：503-87-7
- Empirical Formula: C3H4N2OS
- Molecular Weight: 116.14
- MDL number: MFCD00005277
- EINECS: 207-977-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:19:26
What is 2-Thiohydantoin?
Chemical properties
BROWN CRYSTALLINE POWDER
The Uses of 2-Thiohydantoin
Reactant for synthesis of:• ;Drugs with antidiabetic activity1• ;Barbituric acid and thiohydantoin derivatives with antimicrobial activity2• ;Possible anticancer agents3• ;Fibroblast growth factor receptor 1 kinase inhibitors4• ;HIV-1 integrase inhibitors5Reactant for persilylation6
The Uses of 2-Thiohydantoin
Reactant for synthesis of:
- Drugs with antidiabetic activity
- Barbituric acid and thiohydantoin derivatives with antimicrobial activity
- Possible anticancer agents
- Fibroblast growth factor receptor 1 kinase inhibitors
- HIV-1 integrase inhibitors
Reactant for persilylation
The Uses of 2-Thiohydantoin
2-Thiohydantoin is a useful synthetic intermediate. It is a reactant for synthesis of drugs with antidiabetic activity, barbituric acid and thiohydantoin derivatives with antimicrobial activity, and possible anticancer agents.
What are the applications of Application
2-Thiohydantoin is an inhibitor of Flg
Properties of 2-Thiohydantoin
| Melting point: | 229-231 °C (dec.)(lit.) |
| Density | 1.346 (estimate) |
| vapor density | 4 (vs air) |
| refractive index | 1.6550 (estimate) |
| storage temp. | Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 8.50±0.10(Predicted) |
| color | White |
| CAS DataBase Reference | 503-87-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Imidazolidinone, 2-thioxo-(503-87-7) |
| EPA Substance Registry System | 4-Imidazolidinone, 2-thioxo- (503-87-7) |
Safety information for 2-Thiohydantoin
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for 2-Thiohydantoin
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