2-Picoline-N-oxide
Synonym(s):2-Methylpyridine 1-oxide;2-Picoline N-oxide
- CAS NO.：931-19-1
- Empirical Formula: C6H7NO
- Molecular Weight: 109.13
- MDL number: MFCD00006199
- EINECS: 213-230-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:25:15
What is 2-Picoline-N-oxide?
Chemical properties
light yellow to brown crystalline low melting mass
The Uses of 2-Picoline-N-oxide
2-Picoline N-oxide is used in proteomics research. Also used as pharmaceutical intermediates.
What are the applications of Application
2-Methylpyridine 1-oxide is a useful building block for organic synthesis.
Definition
ChEBI: Picoline N-oxide is a member of methylpyridines and a member of pyridine N-oxides.
Purification Methods
Purify the N-oxide by fractional distillation, and it can be recrystallised from *C6H6/hexane but is hygroscopic. [Bullitt & Maynard J Am Chem Soc 76 1370 1954, Ross et al. J Am Chem Soc 78 3625 1956, IR: Wiley & SlaymAker J Am Chem Soc 79 2233 1957.] The picrate has m 125-126.5o (from EtOH) [Boekelheide & Linn J Am Chem Soc 76 1286 1954]. The phthalate has m 115-116o (from EtOH) [den Hertog et al. Recl Trav Chim Pays-Bas 70 591 1951.]. [Beilstein 20 III/IV 2689, 20/5 V 479.]
Properties of 2-Picoline-N-oxide
| Melting point: | 41-45 °C(lit.) |
| Boiling point: | 259-261 °C |
| Density | 1.1143 (rough estimate) |
| refractive index | 1.5444 (estimate) |
| Flash point: | >230 °F |
| form | powder to lump to clear liquid |
| pka | pK1:1.029(+1) (25°C) |
| color | White or Colorless to Light yellow |
| Water Solubility | soluble |
| Sensitive | Hygroscopic |
| BRN | 106916 |
| CAS DataBase Reference | 931-19-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Pyridine, 2-methyl-, 1-oxide(931-19-1) |
| EPA Substance Registry System | 2-Methylpyridine-1-oxide (931-19-1) |
Safety information for 2-Picoline-N-oxide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Picoline-N-oxide
2-Picoline-N-oxide manufacturer
ALS India Life Sciences Pvt. Ltd
2Y
Phone:+91-8977036378
Whatsapp: +91 8008166674
product: 2-Methylpyridine N-oxide 99.40%
Jaagruthi Lifesciences
1Y
Phone:+91-9848655224
Whatsapp: +91-9848655224
product: 931-19-1 2-Picoline-N-Oxide 98%
Lorven Biologics Pvt Ltd
1Y
Phone:+91-8884110005
Whatsapp: +91-8884110005
product: 931-19-1 2-methyl pyridine N-oxide 98%
SAKEM LLP
1Y
Phone:+91-9676889998
Whatsapp: +91-9676889998
product: 2-Methylpyridine-N-oxide 931-19-1 98%
ASM Organics
Andhra Pradesh
Phone:91-9866122393
Whatsapp: 91-9866122393
product: 2-Methylpyridine 1-oxide
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