2-(Octadecyloxy)ethanol
- CAS NO.：2136-72-3
- Empirical Formula: C20H42O2
- Molecular Weight: 314.55
- MDL number: MFCD00043351
- EINECS: 218-374-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:52:45
What is 2-(Octadecyloxy)ethanol?
The Uses of 2-(Octadecyloxy)ethanol
2-(Octadecyloxy)ethanol is used in preparation of fatty alcohol ethoxylates via etherification of fatty alcohol with ethylene glycol.
Synthesis
Respectively, to take propylene glycol 680mg, sodium hydrogen 2.5g added to 100 ml round bottom flask,THF was added to 10 ml of a solution and stirred for 30 minutes,Then raise the temperature to reflux for 1 hour,And then weigh the bromo-octadecane dispersed in 10 ml of THF by adding a separatory funnel and dropping into the reaction solution,After refluxing the reaction overnight. After completion of the reaction, a saturated sodium chloride solution was added,Dichloromethane extraction three times, combined extract, filter evaporated solvent, crude column chromatography separation,The second band was collected, the resulting product, 550 mg, yield 17.1%.
Properties of 2-(Octadecyloxy)ethanol
| Melting point: | 48-53 °C |
| Boiling point: | 413.1±18.0 °C(Predicted) |
| Density | 0.867±0.06 g/cm3(Predicted) |
| Flash point: | 100 °C |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) |
| form | Solid |
| pka | 14.42±0.10(Predicted) |
| color | White to Off-White |
Safety information for 2-(Octadecyloxy)ethanol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 2-(Octadecyloxy)ethanol
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