2'-O-Methylkurarinone
- CAS NO.：270249-38-2
- Empirical Formula: C27H32O6
- Molecular Weight: 452.54
- MDL number: MFCD21333216
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-29 15:43:00
What is 2'-O-Methylkurarinone?
The Uses of 2'-O-Methylkurarinone
2''-Methoxykurarinone can be used to determine the cytotoxic effects of flavonoids from root of Sophora flavescens in cancer cells.
Definition
ChEBI: (2S)-2'-methoxykurarinone is a dimethoxyflavanone that is (2S)-(-)-kurarinone in which the hydroxy group at position 2' is replaced by a methoxy group. Isolated from the roots of Sophora flavescens, it exhibits cytotoxicity against human myeloid leukemia HL-60 cells. It has a role as a metabolite and an antineoplastic agent. It is a dimethoxyflavanone, a dihydroxyflavanone and a member of 4'-hydroxyflavanones. It is functionally related to a (2S)-(-)-kurarinone.
Properties of 2'-O-Methylkurarinone
| Melting point: | 112-115℃ |
| Boiling point: | 643.6±55.0 °C(Predicted) |
| Density | 1.171±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 7.50±0.40(Predicted) |
| color | Light yellow to brown |
Safety information for 2'-O-Methylkurarinone
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2'-O-Methylkurarinone
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