2-Methylpyrrolidine

CAS NO.：765-38-8
Empirical Formula: C5H11N
Molecular Weight: 85.15
MDL number: MFCD00014491
EINECS: 212-144-3
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:26:03

What is 2-Methylpyrrolidine?

Chemical properties

clear colorless to light yellow liquid

The Uses of 2-Methylpyrrolidine

2-Methylpyrrolidine can be used to produce?2-(2-methylpyrrolidinyl)benzaldehyde?at the temperature of?152°C. It is commonly used as organic reagent.

Definition

ChEBI: 2-methylpyrrolidine is a member of the class of pyrrolidines that is pyrrolidine which is substituted by a methyl group at position 2. It has a role as a plant metabolite.

What are the applications of Application

2-Methylpyrrolidine is an inhibitor of cyclooxygenase-2 (COX-2) and a key component in the preparation of other organic intermediates. 2-Methylpyrrolidine may be used as a guest molecule for the synthesis of nonasil-[4¹5^8], a clatharate compound.

General Description

2-Methylpyrrolidine is a substituted pyrrolidine. It is one of the major bioactive compounds found in Teucrium manghuaense. The hydrodenitrogenation of 2-methylpyrrolidine in the presence of sulfided NiMo/γ-Al₂O₃ catalyst has been studied.

Properties of 2-Methylpyrrolidine

Melting point:	-96.37°C (estimate)
Boiling point:	97-99 °C/744 mmHg (lit.)
Density	0.834 g/mL at 25 °C (lit.)
refractive index	n20/D 1.437(lit.)
Flash point:	37 °F
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
form	Liquid
pka	10.93±0.10(Predicted)
color	Clear colorless to light yellow
Water Solubility	soluble
CAS DataBase Reference	765-38-8(CAS DataBase Reference)
NIST Chemistry Reference	2-Methylpyrrolidine(765-38-8)
EPA Substance Registry System	Pyrrolidine, 2-methyl- (765-38-8)

Safety information for 2-Methylpyrrolidine

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H225:Flammable liquids H302:Acute toxicity,oral H314:Skin corrosion/irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.