2-Methylpyrrolidine
- CAS NO.：765-38-8
- Empirical Formula: C5H11N
- Molecular Weight: 85.15
- MDL number: MFCD00014491
- EINECS: 212-144-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:35:47
What is 2-Methylpyrrolidine?
Chemical properties
clear colorless to light yellow liquid
The Uses of 2-Methylpyrrolidine
2-Methylpyrrolidine can be used to produce?2-(2-methylpyrrolidinyl)benzaldehyde?at the temperature of?152°C. It is commonly used as organic reagent.
Definition
ChEBI: 2-methylpyrrolidine is a member of the class of pyrrolidines that is pyrrolidine which is substituted by a methyl group at position 2. It has a role as a plant metabolite.
What are the applications of Application
2-Methylpyrrolidine is an inhibitor of cyclooxygenase-2 (COX-2) and a key component in the preparation of other organic intermediates. 2-Methylpyrrolidine may be used as a guest molecule for the synthesis of nonasil-[4158], a clatharate compound.
General Description
2-Methylpyrrolidine is a substituted pyrrolidine. It is one of the major bioactive compounds found in Teucrium manghuaense. The hydrodenitrogenation of 2-methylpyrrolidine in the presence of sulfided NiMo/γ-Al2O3 catalyst has been studied.
Properties of 2-Methylpyrrolidine
| Melting point: | -96.37°C (estimate) |
| Boiling point: | 97-99 °C/744 mmHg (lit.) |
| Density | 0.834 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 37 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| form | Liquid |
| pka | 10.93±0.10(Predicted) |
| color | Clear colorless to light yellow |
| Water Solubility | soluble |
| CAS DataBase Reference | 765-38-8(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Methylpyrrolidine(765-38-8) |
| EPA Substance Registry System | Pyrrolidine, 2-methyl- (765-38-8) |
Safety information for 2-Methylpyrrolidine
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H225:Flammable liquids H302:Acute toxicity,oral H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Methylpyrrolidine
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