2'-hydroxy-5'-methoxypropiophenone
- CAS NO.：49710-99-8
- Empirical Formula: C10H12O3
- Molecular Weight: 180.20048
- MDL number: MFCD00598386
- EINECS: 2564400
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-02-12 20:55:48
What is 2'-hydroxy-5'-methoxypropiophenone?
The Uses of 2'-hydroxy-5'-methoxypropiophenone
1-(2-Hydroxy-5-methoxyphenyl)-1-propanone can be used as a new class of transient receptor potential channel TRPA1 and TRPM8 modulators.
Preparation
Preparation by Fries rearrangement of p-methoxyphenyl propionate,
with titanium tetrachloride without solvent at 120° for 1 h (74%)
with aluminium chloride in nitrobenzene at 80–100° for 2 h (41%).
Properties of 2'-hydroxy-5'-methoxypropiophenone
| Melting point: | 47–49°C |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Pale Yellow Low-Melting |
Safety information for 2'-hydroxy-5'-methoxypropiophenone
Computed Descriptors for 2'-hydroxy-5'-methoxypropiophenone
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