2'-hydroxy-5'-methoxypropiophenone

CAS NO.：49710-99-8
Empirical Formula: C10H12O3
Molecular Weight: 180.20048
MDL number: MFCD00598386
EINECS: 2564400
SAFETY DATA SHEET (SDS)
Update Date: 2025-02-12 20:55:48

What is 2'-hydroxy-5'-methoxypropiophenone?

The Uses of 2'-hydroxy-5'-methoxypropiophenone

1-(2-Hydroxy-5-methoxyphenyl)-1-propanone can be used as a new class of transient receptor potential channel TRPA1 and TRPM8 modulators.

Preparation

Preparation by Fries rearrangement of p-methoxyphenyl propionate,
with titanium tetrachloride without solvent at 120° for 1 h (74%)
with aluminium chloride in nitrobenzene at 80–100° for 2 h (41%).

Properties of 2'-hydroxy-5'-methoxypropiophenone

Melting point:	47–49°C
storage temp.	Refrigerator
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
color	Pale Yellow Low-Melting

Safety information for 2'-hydroxy-5'-methoxypropiophenone

Computed Descriptors for 2'-hydroxy-5'-methoxypropiophenone

New Products

Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 2-Bromo-5-hydroxybenzoic acid. 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 4-Fluorophenylglycine 1-N-Boc-3-(aminoethyl)azetidine Dimedone 1-Boc-3-(cyanomethyl)azetidine N-BOC-piperidine-4-carboxylic acid 1-Benzhydrylazetane-3-carbonitrile 5-Amino-2-Hydroxypyridine 2-Amino-5-Iodopyridine 2-BROMOACETYL BROMIDE-D2 METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O DEUTERIUM OXIDE FOR NMR BENZENE-D6 TOLUENE-D3 6-Chloro-pyrimidine-2,4-diamine 3-Oxide 1-Acetyl-4-(4-hydroxyphenyl)piperazine 1-(3-Chlorophenyl)piperazine hydrochloride

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