2-Hydroxy-5-methoxybenzaldehyde
Synonym(s):2-Hydroxy-5-methoxybenzaldehyde;5-Methoxysalicylaldehyde
- CAS NO.：672-13-9
- Empirical Formula: C8H8O3
- Molecular Weight: 152.15
- MDL number: MFCD00003332
- EINECS: 211-589-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:23:14
What is 2-Hydroxy-5-methoxybenzaldehyde?
Chemical properties
clear yellow liquid
The Uses of 2-Hydroxy-5-methoxybenzaldehyde
2-Hydroxy-5-methoxybenzaldehyde is employed to study electroantennogram response of the vine weevil (Otiorhynchus sulcatus F) to a broad range of volatile plant compounds. It plays an important role in the preparation of tetradentate Schiff base compounds. Further, it is used in the preparation 6-methoxy-3-nitro-2H-chromene by using dibutylamine as a reagent.
The Uses of 2-Hydroxy-5-methoxybenzaldehyde
2-Hydroxy-5-methoxybenzaldehyde was used to synthesize radiolabeling precursor desmethyl-PBR06. It was used to study electroantennogram response of the vine weevil (Otiorhynchus sulcatus F.) to a broad range of volatile plant compounds. It was used in the synthesis of tetradentate Schiff base compounds.
Definition
ChEBI: 5-methoxysalicylaldehyde is a member of the class of benzaldehydes carrying hydroxy and methoxy substituents at positions 2 and 5 respectively. It is a member of benzaldehydes, a monomethoxybenzene and a member of phenols. It is functionally related to a salicylaldehyde.
General Description
2-Hydroxy-5-methoxybenzaldehyde has acaricidal activity against Tyrophagus putrescentiae.
Properties of 2-Hydroxy-5-methoxybenzaldehyde
| Melting point: | 4 °C (lit.) |
| Boiling point: | 103 °C/2.5 mmHg (lit.) |
| Density | 1.219 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | Store below +30°C. |
| form | Liquid |
| pka | 8.66±0.18(Predicted) |
| color | Clear yellow |
| Water Solubility | Miscible with chloroform. Slightly miscible with water. |
| Sensitive | Air Sensitive |
| BRN | 1100532 |
| CAS DataBase Reference | 672-13-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzaldehyde, 2-hydroxy-5-methoxy-(672-13-9) |
Safety information for 2-Hydroxy-5-methoxybenzaldehyde
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-Hydroxy-5-methoxybenzaldehyde
| InChIKey | FZHSPPYCNDYIKD-UHFFFAOYSA-N |
2-Hydroxy-5-methoxybenzaldehyde manufacturer
SAKEM LLP
INNOVATIVE LABS
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