2-Hydrazinopyrazine
- CAS NO.：54608-52-5
- Empirical Formula: C4H6N4
- Molecular Weight: 110.12
- MDL number: MFCD04114555
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-24 18:13:52
What is 2-Hydrazinopyrazine?
Chemical properties
Pale yellow solid
The Uses of 2-Hydrazinopyrazine
Triazolo[4,3-a]pyrazine 7-oxide, 3-β-D-ribofuranosyl-1,2,4-triazolo[4,3-a]pyrazine, monohydrazones of pyridine, pyrazine, phenylglyoxal were synthesised from 2-Hydrazinopyrazine.
What are the applications of Application
2-Hydrazinopyrazine is used as a reagent in the synthesis of Sitagliptin (S491000, H3PO4) and its analogs. Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor that has recently been approved for the therapy of type II diabetes.
Properties of 2-Hydrazinopyrazine
| Melting point: | 109-113℃ |
| Boiling point: | 246.3±23.0 °C(Predicted) |
| Density | 1.39±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| pka | 5.10±0.20(Predicted) |
| form | Solid |
| color | Yellow |
| Water Solubility | Slightly soluble in water. |
Safety information for 2-Hydrazinopyrazine
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-Hydrazinopyrazine
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