2-Dimethylaminopyridine
- CAS NO.：5683-33-0
- Empirical Formula: C7H10N2
- Molecular Weight: 122.17
- MDL number: MFCD00006261
- EINECS: 227-147-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:05
What is 2-Dimethylaminopyridine?
Chemical properties
Clear colorless to pale yellow liquid
The Uses of 2-Dimethylaminopyridine
2-(Dimethylamino)pyridine in toluene at room temperature in the presence of 1.1 equivalent of methyl trifluoromethanesulfonate forms (2-pyridyl)-trimethylammonium trifluoromethanesulfonate salt. It is used as a model substrate in the preparation of chelate carbene via cyclometalation, H2 loss and reversible α-elimination.
General Description
2-(Dimethylamino)pyridine is a clear, colorless to light yellow liquid.
Safety Profile
A poison by intravenous route. When heated to decomposition it emits toxic vapors of NOx
Properties of 2-Dimethylaminopyridine
| Melting point: | 182°C |
| Boiling point: | 191 °C(lit.) |
| Density | 0.984 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 167 °F |
| storage temp. | Store below +30°C. |
| form | Liquid |
| pka | 7.04±0.10(Predicted) |
| color | Clear colorless to pale yellow |
| Water Solubility | Soluble in water. |
| BRN | 110353 |
| CAS DataBase Reference | 5683-33-0(CAS DataBase Reference) |
| NIST Chemistry Reference | N,N-Dimethyl-2-pyridinamine(5683-33-0) |
Safety information for 2-Dimethylaminopyridine
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Dimethylaminopyridine
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