2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate

CAS NO.：51-68-3
Empirical Formula: C12H16ClNO3
Molecular Weight: 257.71
MDL number: MFCD00242773
EINECS: 200-116-3
SAFETY DATA SHEET (SDS)
Update Date: 2024-03-18 13:30:28

What is 2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate?

Chemical properties

The commodity of meclofenoxate is hydrochloride (C12H16CINO3·HCL, [3685-84-5]), also known as Lucidril, Brenal, etc. It is a white crystalline powder with a melting point of 135-139°C. Easily soluble in water, insoluble in ether, benzene and chloroform. The taste is sour and bitter, and it is easy to decompose and fail when exposed to moisture.

The Uses of 2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate

Meclofenoxate is a central nervous system stimulant. It mainly acts on the cerebral cortex, promotes the redox of brain cells, increases the utilization of sugar, can regulate the metabolism of nerve cells, and promote the excitation of the nervous system in a state of inhibition. It is an effective drug for stimulating the spirit and inhibiting fatigue.

Definition

ChEBI: Meclofenoxate is a monocarboxylic acid.

Side Effects

Occasionally can cause excitement, insomnia, blood pressure changes, vascular pain or fatigue.

Synthesis

Meclofenoxate can be prepared by esterification of p-chlorophenoxyacetic acid, dimethylaminoethanol, m-xylene and p-toluenesulfonic acid.

Properties of 2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate

Melting point:	138-140 °C
Boiling point:	180 °C(Press: 9-10 Torr)
Density	1.2038 (rough estimate)
refractive index	1.5200 (estimate)
pka	8.17±0.28(Predicted)
NIST Chemistry Reference	Meclofenoxate(51-68-3)