2-(DIFLUOROMETHOXY)BENZALDEHYDE
- CAS NO.：71653-64-0
- Empirical Formula: C8H6F2O2
- Molecular Weight: 172.13
- MDL number: MFCD00042251
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-14 15:28:00
What is 2-(DIFLUOROMETHOXY)BENZALDEHYDE?
The Uses of 2-(DIFLUOROMETHOXY)BENZALDEHYDE
2-(Difluoromethoxy)benzaldehyde is an important raw material used as an intermediate in the preparation of pharmaceuticals, agrochemicals, and dyestuffs. It is also involved in the preparation of 4-(2-difluoromethoxyphenyl)- substituted 1,4-dihydropyridine 3,5-diesters.
The Uses of 2-(DIFLUOROMETHOXY)BENZALDEHYDE
2-(Difluoromethoxy)benzaldehyde may be used as a starting reagent in the synthesis of the following compounds:
- 2-[2-(difluoromethoxy)benzylidene]methyl acetoacetate
- 3-(2-cyanoethyl) 5-(2-propoxyethyl) 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
- 2-propoxyethyl 5-cyano-4-[2-(difluoromethoxy)phenyl]-2-methyl-6-thioxo-1,4,5,6-tetrahydropyridine-3-carboxylate
- methyl 5-cyano-4-(2-difluoromethoxyphenyl)-2-methyl-6-thioxo-1,4,5,6-tetrahydropyridine-3-carboxylate
General Description
2-(Difluoromethoxy)benzaldehyde is an ortho-difluoromethoxy substituted benzaldehyde.
Properties of 2-(DIFLUOROMETHOXY)BENZALDEHYDE
| Boiling point: | 216 °C (lit.) |
| Density | 1.3 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 224 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Miscible with 2-propanol and acetic acid. |
| form | clear liquid |
| color | Colorless to Light yellow to Light orange |
| Sensitive | Air Sensitive |
| BRN | 389068 |
| CAS DataBase Reference | 71653-64-0(CAS DataBase Reference) |
Safety information for 2-(DIFLUOROMETHOXY)BENZALDEHYDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-(DIFLUOROMETHOXY)BENZALDEHYDE
New Products
2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 2-fluoro-4-iodoaniline 4-Iodo-3,5-dimethylbenzonitrile Atorvastatin amide impurity/Atorvastatin EP Impurity F(Calcium Salt) Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine 6-bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-Fluoro-4-nitrotoluene 1-(2-amino-5-hydroxy phenyl)propan-1-one (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 3-(Dimethylamino)benzoic acid 2-Amino-5-chloropyridine 4-(Methylamino)-3-nitrobenzoic Acid 5-Chloro-2-Nitroaniline 3,5-dibenzyloxy Acetophenone 2,4-Diamino-6-hydroxypyrimidine 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy BenzylcyanideRelated products of tetrahydrofuran
![[2-(TRIFLUOROMETHOXY)PHENYL][4-(TRIFLUOROMETHOXY)PHENYL]METHANONE](https://img.chemicalbook.in/CAS/GIF/98566-94-0.gif)
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