2-CHLOROETHYL ISOTHIOCYANATE

CAS NO.：6099-88-3
Empirical Formula: C3H4ClNS
Molecular Weight: 121.59
MDL number: MFCD00041125
EINECS: 000-000-0
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-27 22:44:03

What is 2-CHLOROETHYL ISOTHIOCYANATE?

Chemical properties

clear yellow liquid

The Uses of 2-CHLOROETHYL ISOTHIOCYANATE

2-Chloroethyl isothiocyanate is used as a reagent to synthesize Zanamivir (Z148000), a compound that acts as a selective inhibitor of Influenza A and B virus neuraminidases. 2-Chloroethyl isothiocyanate is also used as a reagent to synthesize heterocyclic compounds (e.g. Fluorescein 6-Isothiocyanate [F485705]).

Properties of 2-CHLOROETHYL ISOTHIOCYANATE

Melting point:	172 °C
Boiling point:	80 °C13 mm Hg(lit.)
Density	1.265 g/mL at 25 °C(lit.)
refractive index	n20/D 1.556(lit.)
Flash point:	110 °F
storage temp.	Flammables area
form	Liquid
Specific Gravity	1.265
color	Clear yellow
Sensitive	Moisture Sensitive
BRN	605585
CAS DataBase Reference	6099-88-3(CAS DataBase Reference)

Safety information for 2-CHLOROETHYL ISOTHIOCYANATE

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H226:Flammable liquids H302:Acute toxicity,oral H312:Acute toxicity,dermal H314:Skin corrosion/irritation H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..…