2-Chloroanisole
- CAS NO.:766-51-8
- Empirical Formula: C7H7ClO
- Molecular Weight: 142.58
- MDL number: MFCD00000557
- EINECS: 212-167-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-10 10:27:30
What is 2-Chloroanisole?
Chemical properties
CLEAR LIGHT YELLOW LIQUID
The Uses of 2-Chloroanisole
2-Chloroanisole was used in headspace solid-phase microextraction method for the determination of haloanisoles in wine and spirit samples.
Synthesis Reference(s)
Journal of the American Chemical Society, 96, p. 2252, 1974 DOI: 10.1021/ja00814a045
The Journal of Organic Chemistry, 41, p. 732, 1976 DOI: 10.1021/jo00866a043
General Description
2-Chloroanisole undergoes acetylation with acetic anhydride over large pore zeolites to give 4-acetyl-2-chloroanisole.
Properties of 2-Chloroanisole
| Melting point: | -26.8°C |
| Boiling point: | 195-196 °C (lit.) |
| Density | 1.123 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 169 °F |
| storage temp. | Sealed in dry,Room Temperature |
| form | Liquid |
| color | Clear light yellow |
| Water Solubility | 0.49g/L(25 ºC) |
| BRN | 2042179 |
| CAS DataBase Reference | 766-51-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1-chloro-2-methoxy-(766-51-8) |
| EPA Substance Registry System | o-Chloroanisole (766-51-8) |
Safety information for 2-Chloroanisole
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H227:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..… |
Computed Descriptors for 2-Chloroanisole
2-Chloroanisole manufacturer
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