2-Chloro-4-amino-6,7-dimethoxyquinazoline
Synonym(s):2-Chloro-6,7-dimethoxy-4-quinazolinamine;4-Amino-2-chloro-6,7-dimethoxyquinazoline
- CAS NO.：23680-84-4
- Empirical Formula: C10H10ClN3O2
- Molecular Weight: 239.66
- MDL number: MFCD00051734
- EINECS: 245-821-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 05:41:41
What is 2-Chloro-4-amino-6,7-dimethoxyquinazoline?
Chemical properties
Off-White Solid
The Uses of 2-Chloro-4-amino-6,7-dimethoxyquinazoline
Intermediate in the production on Terazosin.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 20, p. 146, 1977 DOI: 10.1021/jm00211a031
Flammability and Explosibility
Non flammable
Properties of 2-Chloro-4-amino-6,7-dimethoxyquinazoline
| Melting point: | 262-268 °C (dec.)(lit.) |
| Boiling point: | 374.0±42.0 °C(Predicted) |
| Density | 1.5062 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.5500 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO (Sparingly, Heated), Methanol (Slightly, Heated) |
| form | neat |
| pka | 4.35±0.30(Predicted) |
| color | White to Off-White |
| Water Solubility | 1.418g/L at 25℃ |
| BRN | 747463 |
| CAS DataBase Reference | 23680-84-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Amino-2-chloro-6,7-dimethoxyquinazoline(23680-84-4) |
Safety information for 2-Chloro-4-amino-6,7-dimethoxyquinazoline
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Chloro-4-amino-6,7-dimethoxyquinazoline
2-Chloro-4-amino-6,7-dimethoxyquinazoline manufacturer
SAKEM LLP
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Phone:+91-9676889998
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product: 4-Amino-2-chloro-6,7-dimethoxyquinazoline 23680-84-4 98%
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![2,2'-(1,4-Piperazinediyl)bis[6,7-diMethoxy-4-quinazolinaMine]](https://img.chemicalbook.in/CAS/GIF/102839-00-9.gif)
![1-[4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone](https://img.chemicalbook.in/CAS/GIF/109678-71-9.gif)
Methanone](https://img.chemicalbook.in/CAS/GIF/105356-90-9.gif)
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