2-Chloro-1,3,2-dioxaphospholane
Synonym(s):Cyclic ethylene chlorophosphite;Cyclic ethylene phosphorochloridite;Ethylene chlorophosphite;Ethylene glycol chlorophosphite
- CAS NO.：822-39-9
- Empirical Formula: C2H4ClO2P
- Molecular Weight: 126.48
- MDL number: MFCD00014511
- EINECS: 212-499-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 05:23:23
What is 2-Chloro-1,3,2-dioxaphospholane?
Chemical properties
Clear Colourless Oil
The Uses of 2-Chloro-1,3,2-dioxaphospholane
Ethylene chlorophosphite acts as a phosphitylating agent involved in the preparation of phosphocholine and spirophosphoranes. For example, it is used in the phosphorylation of p-tert-butyl(thia)calixarenes.
The Uses of 2-Chloro-1,3,2-dioxaphospholane
Highly reactive cyclic phosphitylating reagent which provides fast coupling rates, and hydrolytic cleavage occurs more readily than with acyclic analogs
Properties of 2-Chloro-1,3,2-dioxaphospholane
| Melting point: | -28°C(lit.) |
| Boiling point: | 62 °C/20 mmHg (lit.) |
| Density | 1.422 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 158 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly) |
| form | clear liquid |
| color | Colorless to Light yellow |
| Sensitive | Moisture Sensitive |
| BRN | 506179 |
| Stability: | Extremely Moisture Sensitive |
| CAS DataBase Reference | 822-39-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethylene chlorophosphite(822-39-9) |
| EPA Substance Registry System | 1,3,2-Dioxaphospholane, 2-chloro- (822-39-9) |
Safety information for 2-Chloro-1,3,2-dioxaphospholane
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Chloro-1,3,2-dioxaphospholane
New Products
Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) BOC Piperazine 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 Trans,trans muconic acid HC Blue-16 4-Amino-2-chloro-6,7-dimethoxyquinazoline Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 2,3-Dimethoxypyridine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
You may like
-
2-Chloro-1,3,2-dioxaphospholane CAS 822-39-9View Details
822-39-9 -
2-Chloro-1,3,2-dioxaphospholane CAS 822-39-9View Details
822-39-9 -
Product IntroductionView Details -
Product InrtroductionView Details -
DGO24View Details -
DGO25View Details -
DGO29View Details -
DGO32View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.