2-Bromobiphenyl

CAS NO.：2052-07-5
Empirical Formula: C12H9Br
Molecular Weight: 233.1
MDL number: MFCD00000065
EINECS: 218-141-3
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-04 14:24:59

What is 2-Bromobiphenyl?

Physical properties

2-Bromobiphenyl has a melting point of 1.5-2 °C, so it is a colorless liquid at room temperature. It boils at 297-298 °C. Its density at 25℃ is 1.352 g/mL. In general, 2-bromobiphenyls are stable, but they are not compatible with oxidants.

The Uses of 2-Bromobiphenyl

It is used as an intermediate of organic synthesis and pharmaceutical. It also can react with norborn-2-ene to get 5-phenyl-1,2,3,4,4a,8b-hexahydro-1,4-methanobiphenylene, in synthesis of a novel trispirocyclic hydrocarbon. It is used as a reference compound to investigate extraction efficiency of solid-phase micro extraction fibers, based on methacrylic acid-trimethylolpropanetrimethacrylate copolymers.

What are the applications of Application

2-Bromobiphenyl is a reference compound to investigate extraction efficiency of solid-phase microextraction fibers

Synthesis Reference(s)

The Journal of Organic Chemistry, 44, p. 3037, 1979 DOI: 10.1021/jo01331a016
Tetrahedron Letters, 21, p. 845, 1980 DOI: 10.1016/S0040-4039(00)71521-8

General Description

Clear liquid. Insoluble in water.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Bromobiphenyl is sensitive to light. Low reactivity.

Fire Hazard

Flash point data for 2-Bromobiphenyl are not available. 2-Bromobiphenyl is probably combustible.

Properties of 2-Bromobiphenyl

Melting point:	1.5-2 °C(lit.)
Boiling point:	297-298 °C(lit.)
Density	1.352 g/mL at 25 °C(lit.)
refractive index	n20/D 1.628(lit.)
Flash point:	113 °C
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Sparingly, Heated), Methanol (Slightly)
form	Liquid
Specific Gravity	1.352
color	Clear colorless
Water Solubility	Insoluble
BRN	1863156
Stability:	Stable, but light sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference	2052-07-5(CAS DataBase Reference)
NIST Chemistry Reference	1,1'-Biphenyl, 2-bromo-(2052-07-5)
EPA Substance Registry System	2-Bromobiphenyl (2052-07-5)

Safety information for 2-Bromobiphenyl

Signal word	Danger
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H317:Sensitisation, Skin H372:Specific target organ toxicity, repeated exposure H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.