2-Bromo-2'-nitroacetophenone

Synonym(s):2′-Nitrophenacyl bromide

CAS NO.：6851-99-6
Empirical Formula: C8H6BrNO3
Molecular Weight: 244.04
MDL number: MFCD00010294
SAFETY DATA SHEET (SDS)
Update Date: 2026-06-04 16:00:12

What is 2-Bromo-2'-nitroacetophenone?

Chemical properties

White to pale yellow crystalline powder

The Uses of 2-Bromo-2'-nitroacetophenone

2-Bromo-2'-nitroacetophenone is used in the novel synthesis of 5-pyridylindolizine derivatives.

The Uses of 2-Bromo-2'-nitroacetophenone

2-Bromo-2′-nitroacetophenone, an electroactive derivative-forming reagent, was used as a precolumn reagent for preparing prostaglandin derivatives.

Synthesis Reference(s)

Canadian Journal of Chemistry, 61, p. 400, 1983 DOI: 10.1139/v83-072
The Journal of Organic Chemistry, 49, p. 438, 1984 DOI: 10.1021/jo00177a010

Properties of 2-Bromo-2'-nitroacetophenone

Melting point:	55-57 °C(lit.)
Boiling point:	335.7±17.0 °C(Predicted)
Density	1.671±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform, Methanol
form	Crystalline Powder
color	White to pale yellow
λmax	262nm(EtOH)(lit.)
CAS DataBase Reference	6851-99-6(CAS DataBase Reference)

Safety information for 2-Bromo-2'-nitroacetophenone

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.