2-Benzylpyridine

Synonym(s):2-Benzylpyridine

CAS NO.：101-82-6
Empirical Formula: C12H11N
Molecular Weight: 169.22
MDL number: MFCD00006352
EINECS: 202-979-1
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:13:03

What is 2-Benzylpyridine?

Chemical properties

2-Benzylpyridine is a clear yellow to brown liquid or pale straw-colored oily liquid. Poorly soluble in water, soluble in alcohol and oils. Powerful green vegetable type odor with considerable resemblance to the odor of raw stringbeans (or “Haricots-verts”). The warm-herbaceous undertone is often accompanied by traces of a protein-like terminal note, possibly impurity-odor. Moderate tenacity.

The Uses of 2-Benzylpyridine

2-Benzylpyridine is a benzylpyridine with antifungal properties. 2-Benzylpyridine is also used as a chromogenic reagent for micro determination of Molybednum.

The Uses of 2-Benzylpyridine

2-Benzylpyridine is used in organic synthesis.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 24, p. 1205, 1987 DOI: 10.1002/jhet.5570240453
Tetrahedron Letters, 24, p. 889, 1983 DOI: 10.1016/S0040-4039(00)81556-7

Safety Profile

Moderately toxic by subcutaneousroute. When heated to decomposition it emits toxicvapors of NOx.

Purification Methods

Dry it with NaOH for several days, then distil it from CaO under reduced pressure, and redistil the middle fraction. [Beilstein 20/7 V 556.]

Properties of 2-Benzylpyridine

Melting point:	8-10 °C (lit.)
Boiling point:	276 °C (lit.)
Density	1.054 g/mL at 25 °C (lit.)
refractive index	n20/D 1.579(lit.)
Flash point:	257 °F
storage temp.	Store below +30°C.
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	5.13(at 25℃)
form	neat
color	yellow
Water Solubility	insoluble
BRN	115875
CAS DataBase Reference	101-82-6(CAS DataBase Reference)
NIST Chemistry Reference	Pyridine, 2-(phenylmethyl)-(101-82-6)
EPA Substance Registry System	Pyridine, 2-(phenylmethyl)- (101-82-6)

Safety information for 2-Benzylpyridine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.