2-Amino-4-nitrophenol
Synonym(s):2-Hydroxy-5-nitroaniline
- CAS NO.:99-57-0
- Empirical Formula: C6H6N2O3
- Molecular Weight: 154.12
- MDL number: MFCD00007695
- EINECS: 202-767-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-10 10:27:30
What is 2-Amino-4-nitrophenol?
Chemical properties
OCHRE CRYSTALLINE POWDER
The Uses of 2-Amino-4-nitrophenol
2-Amino-4-nitrophenol is used in preparing some mordant dyes and in some hair dyes.
The Uses of 2-Amino-4-nitrophenol
An aromatic constituent found in hair dyes and other cosmetic products with very low levels of mutagenic activity.
Definition
ChEBI: 2-Amino-4-nitrophenol is a member of 4-nitrophenols.
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 3, p. 82, 1955
The Journal of Organic Chemistry, 45, p. 4992, 1980 DOI: 10.1021/jo01312a039
General Description
Orange prisms or yellow powder. No odor.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Oxidation of 2-Amino-4-nitrophenol may occur in the presence of air and violent decomposition may occur if 2-Amino-4-nitrophenol is allowed to dry out completely at elevated temperatures. 2-Amino-4-nitrophenol is stable when stored protected from light and under nitrogen for two weeks at temperatures up to 140° F, and storage under nitrogen for up to 24 weeks at room temperature (77° F) should produce no loss of stability. 2-Amino-4-nitrophenol is incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizing agents. 2-Amino-4-nitrophenol is also incompatible with iron.
Fire Hazard
Flash point data for 2-Amino-4-nitrophenol are not available. 2-Amino-4-nitrophenol is probably combustible.
Flammability and Explosibility
Non flammable
Purification Methods
Crystallise the phenol from water. [Beilstein 13 IV 896.]
Properties of 2-Amino-4-nitrophenol
| Melting point: | 140-143 °C (lit.) |
| Boiling point: | 322.46°C (rough estimate) |
| Density | 1.3617 (estimate) |
| vapor pressure | 0.005Pa at 25℃ |
| refractive index | 1.6890 (rough estimate) |
| Flash point: | 100 °C |
| storage temp. | Refrigerator, Under Inert Atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 6.82±0.22(Predicted) |
| color | Dark Yellow to Brown |
| Water Solubility | slightly soluble |
| BRN | 776533 |
| CAS DataBase Reference | 99-57-0(CAS DataBase Reference) |
| IARC | 3 (Vol. 57) 1993 |
| EPA Substance Registry System | 2-Amino-4-nitrophenol (99-57-0) |
Safety information for 2-Amino-4-nitrophenol
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Amino-4-nitrophenol
2-Amino-4-nitrophenol manufacturer
ASM Organics
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate 3,6-Dichloropyridazine Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane 4-Morpholinoaniline 2-Chloromethyl-6-methyl-pyridine 1-Indanone tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 2-Pyridinecarboxaldehdye 6-Methyl-2-pyridinemethanol 4-Bromo-2-fluoro-N-methylbenzamide 3-Azetidinecarboxylic acid N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-6-methoxypyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide (R)-4-Boc-morpholine-3-carboxylic acid (Required high chiral purity NLT:99.5%) Tetrahydro-3-(2-methyl-2- nitropropyl)-2H-pyran-2-one 3-Bromo-2-fluorobenzonitrile Desoximetasone Boron Triiodide Nicotinic acid RAPAMYCIN Pentachlorobenzonitrile BudesonideRelated products of tetrahydrofuran








You may like
-
2-Amino-4-nitrophenol CAS 99-57-0View Details
99-57-0 -
2-Amino-4-Nitrophenol Cas: 99-57-0, Packaging Type: DrumView Details
99-57-0 -
Industrial 4-Nitro-2-Aminophenol PowderView Details
99-57-0 -
4NapView Details
99-57-0 -
2-Chlorophenyl diphenyl chloromethane 99%View Details
42074-68-0 -
6-(chloromethyl)pteridine-2,4-diamine monohydrochloride 82778?08?3 99%View Details
82778?08?3 -
729559-09-5 [N(E)]-N-Ethylidene-2-methyl-2-propanesulfinamide 99%View Details
729559-09-5 -
2709271-25-8 99%View Details
2709271-25-8

