2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
- CAS NO.：14665-75-9
- Empirical Formula: C8H9NO2.ClH
- Molecular Weight: 187.625
- MDL number: MFCD11974302
- Update Date: 2025-10-14 17:28:58
What is 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE?
The Uses of 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
2-Amino-3’-hydroxy-acetophenone Hydrochloride is a reactant in the synthesis of TRPM8 modulators.
Preparation
Preparation by hydrolysis of m-(benzoyloxy)- a-amino-acetophenone hydrochloride (SM) (m.p. 202–205°) with refluxing 10% hydrochloric acid (quantitative yield), for 2 h (80%); ? with 37% hydrochloric acid in chlorobenzene at 90° for 3 h (90%). SM was obtained by reaction of hexamethylenetetramine with m-(benzoyloxy)- a-bromoacetophenone (m.p. 162°) in ethanol in the presence of 37% hydrochloric acid for 6 h at r.t. (75%).
Properties of 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
| Melting point: | 221–222°C |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | Pale Beige to Brown |
Safety information for 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
Computed Descriptors for 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
New Products
DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran
![3-[(1S)-2-[benzyl(methyl)amino]-1-hydroxyethyl]phenol](https://img.chemicalbook.in/CAS/20200119/GIF/286426-31-1.gif)
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