2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
- CAS NO.：14665-75-9
- Empirical Formula: C8H9NO2.ClH
- Molecular Weight: 187.625
- MDL number: MFCD11974302
- Update Date: 2025-10-14 17:28:58
What is 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE?
The Uses of 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
2-Amino-3’-hydroxy-acetophenone Hydrochloride is a reactant in the synthesis of TRPM8 modulators.
Preparation
Preparation by hydrolysis of m-(benzoyloxy)- a-amino-acetophenone hydrochloride (SM) (m.p. 202–205°) with refluxing 10% hydrochloric acid (quantitative yield), for 2 h (80%); ? with 37% hydrochloric acid in chlorobenzene at 90° for 3 h (90%). SM was obtained by reaction of hexamethylenetetramine with m-(benzoyloxy)- a-bromoacetophenone (m.p. 162°) in ethanol in the presence of 37% hydrochloric acid for 6 h at r.t. (75%).
Properties of 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
| Melting point: | 221–222°C |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | Pale Beige to Brown |
Safety information for 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
Computed Descriptors for 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 1-AMino-cyclobutaneMethanol HCl TETRABUTYLAMMONIUM CYANIDE 3-Amino-3-(3-fluorophenyl)propanoic acid 3-Amino-3-(4-methylphenyl)propionic acid 3-AMINO-3-(3-CHLORO-PHENYL)-PROPIONIC ACID Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 4 - fluoro- 2 - methoxy- 5 - nitroaniline 1-(2-amino-5-hydroxy phenyl)propan-1-one tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-amino-5-nitrobenzonitrile (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanideRelated products of tetrahydrofuran
![3-[(1S)-2-[benzyl(methyl)amino]-1-hydroxyethyl]phenol](https://img.chemicalbook.in/CAS/20200119/GIF/286426-31-1.gif)
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