2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
- CAS NO.：14665-75-9
- Empirical Formula: C8H9NO2.ClH
- Molecular Weight: 187.625
- MDL number: MFCD11974302
- Update Date: 2025-10-14 17:28:58
What is 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE?
The Uses of 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
2-Amino-3’-hydroxy-acetophenone Hydrochloride is a reactant in the synthesis of TRPM8 modulators.
Preparation
Preparation by hydrolysis of m-(benzoyloxy)- a-amino-acetophenone hydrochloride (SM) (m.p. 202–205°) with refluxing 10% hydrochloric acid (quantitative yield), for 2 h (80%); ? with 37% hydrochloric acid in chlorobenzene at 90° for 3 h (90%). SM was obtained by reaction of hexamethylenetetramine with m-(benzoyloxy)- a-bromoacetophenone (m.p. 162°) in ethanol in the presence of 37% hydrochloric acid for 6 h at r.t. (75%).
Properties of 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
| Melting point: | 221–222°C |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | Pale Beige to Brown |
Safety information for 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
Computed Descriptors for 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloropyridazine 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane m-Tolualdehyde p-Anisaldehyde 2-Bromobenzaldehyde 4-Fluorobenzaldehyde 1-Propyl-4-piperidone 3-Amino-3-(3-fluorophenyl)propanoic acid 6-Methyl-2-pyridinemethanol 2-Pyridinecarboxaldehdye tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 1-Indanone 2-Chloromethyl-6-methyl-pyridine 4-Morpholinoaniline Abiraterone Ethyl Ether 1-nitro-3,5-dimethyl adamantine (NMEM) Vardenafil Bis-sulphonamide(Dimer) 3-(2-aminoethyl) benzene sulfonamide Nabumetone Impurity 5 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran
![3-[(1S)-2-[benzyl(methyl)amino]-1-hydroxyethyl]phenol](https://img.chemicalbook.in/CAS/20200119/GIF/286426-31-1.gif)
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