2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
- CAS NO.：14665-75-9
- Empirical Formula: C8H9NO2.ClH
- Molecular Weight: 187.625
- MDL number: MFCD11974302
- Update Date: 2026-05-28 01:04:30
What is 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE?
The Uses of 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
2-Amino-3’-hydroxy-acetophenone Hydrochloride is a reactant in the synthesis of TRPM8 modulators.
Preparation
Preparation by hydrolysis of m-(benzoyloxy)- a-amino-acetophenone hydrochloride (SM) (m.p. 202–205°) with refluxing 10% hydrochloric acid (quantitative yield), for 2 h (80%); ? with 37% hydrochloric acid in chlorobenzene at 90° for 3 h (90%). SM was obtained by reaction of hexamethylenetetramine with m-(benzoyloxy)- a-bromoacetophenone (m.p. 162°) in ethanol in the presence of 37% hydrochloric acid for 6 h at r.t. (75%).
Properties of 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
| Melting point: | 221–222°C |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | Pale Beige to Brown |
Safety information for 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
Computed Descriptors for 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
New Products
9-Mesityl-10-methylacridinium perchlorate Sulfapyridine Fmoc-OSu (R)-(-)-2-Amino-1-propanol Cyclobutanone 5-bromo-4-fluoro-2-nitrobenzaldehyde 4 pentyn 1 ol N-Vinylformamide Phenethyl cinnamate Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 4-Nitrobenzotrifluoride 2-Pentyn-1-oL N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
![3-[(1S)-2-[benzyl(methyl)amino]-1-hydroxyethyl]phenol](https://img.chemicalbook.in/CAS/20200119/GIF/286426-31-1.gif)
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