2-(4-Methylphenyl)ethanol

CAS NO.：699-02-5
Empirical Formula: C9H12O
Molecular Weight: 136.19
MDL number: MFCD00002904
EINECS: 211-824-7
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

What is 2-(4-Methylphenyl)ethanol?

Description

2-(4-Methylphenyl)ethanol, also known as 4-Methylphenethyl alcohol, 2-(p-Tolyl)ethanol, is an oily liquid that can promote bile secretion and protect the liver. It is capable of transporting fat from the liver to the extrahepatic fat pool via the bloodstream and has demonstrated a significant inhibitory effect on liver cell destruction caused by alcoholism.

Chemical properties

Colorless to faintly Light yellow to Light orange clear liquid.

The Uses of 2-(4-Methylphenyl)ethanol

4-Methylphenethyl alcohol was used in the determination of adducts of 1,2- and 1,4-benzoquinone with cysteine residues of hemoglobin and albumin.

Preparation

To prepare 2-(4-Methylphenyl)ethanol, start with 4'-Methylacetophenone as the raw material. Reduce it to 4-methyl-α-phenylethanol using sodium borohydride in ethanol. Mix nicotinic acid with phosphorus oxychloride in pyridine to create nicotinyl chloride. Without separation, add the nicotinyl chloride to the 4-methyl-α-phenylethanol and esterify it into 2-(4-Methylphenyl)ethanol.?

Properties of 2-(4-Methylphenyl)ethanol

Boiling point:	244-245 °C(lit.)
Density	0.978 g/mL at 25 °C(lit.)
refractive index	n20/D 1.526(lit.)
Flash point:	225 °F
storage temp.	Sealed in dry,Room Temperature
form	clear liquid
pka	14.92±0.10(Predicted)
Specific Gravity	0.978
color	Colorless to Light yellow to Light orange
Odor	at 100.00 %. floral balsamic rose green
InChI	InChI=1S/C9H12O/c1-8-2-4-9(5-3-8)6-7-10/h2-5,10H,6-7H2,1H3
CAS DataBase Reference	699-02-5(CAS DataBase Reference)
EPA Substance Registry System	Benzeneethanol, 4-methyl- (699-02-5)

Safety information for 2-(4-Methylphenyl)ethanol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.