2-(3,4-Dichlorophenyl)-4-fluoroaniline
- CAS NO.：877179-04-9
- Empirical Formula: C12H8Cl2FN
- Molecular Weight: 256.1
- MDL number: MFCD19440920
- EINECS: 700-287-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-16 09:54:54
What is 2-(3,4-Dichlorophenyl)-4-fluoroaniline?
Synthesis
8.15 g (97%, 0.042 mol) of 3,4-dichlorophenylboronic acid are initially charged in 50 g of water and 50 g toluene. Subsequently, 18.7 g (0.085 mol) of potassium phosphate and 8.2 g (98%, 0.042 mol) of 2-bromo-4-fluoroaniline are added. After blanketing with nitrogen, 0.014 g (0.00002 mol) of 1,1'-bis(di-test-butyl phosphine) ferrocene palladium dichloride is added, and the mixture is stirred for two hours at 79-81° C. The organic phase is separated and evaporated under reduced pressure, leaving 10.5 g of an oil-crystallized 2-(3,4-Dichlorophenyl)-4-fluoroaniline. 
Properties of 2-(3,4-Dichlorophenyl)-4-fluoroaniline
| Boiling point: | 357℃ at 101.3kPa |
| Density | 1.47 at 20℃ |
| storage temp. | 2-8°C |
| pka | 3.22±0.10(Predicted) |
Safety information for 2-(3,4-Dichlorophenyl)-4-fluoroaniline
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-(3,4-Dichlorophenyl)-4-fluoroaniline
2-(3,4-Dichlorophenyl)-4-fluoroaniline manufacturer
New Products
2,6-Piperidinedione, 3-hydroxy-1-[(4-methoxyphenyl)methyl]- 3-(4-bromo-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione 4-Hydroxy-6-methyl-1-(4-methylphenyl)-2-naphthalenecarboxylic acid 2,3-Difluoro-6-methoxybenzyl Chloride KT-474 2-(6-(benzyloxy)-3,4-dihydronaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 3-Oxocyclobutanecarboxylic acid 5-Bromo-2-iodo pyridine Benzofuran-6-carboxylic acid (BFA) 3-Bromo-2-Ethoxy-5-Nitropyridine 3,6-Dichloro-2-Methylpyridine 2-Amino-5-Bromo-3-IodopyridineYou may like
-
2-(3,4-DICHLOROPHENYL)-4-FLUOROANILINE 877179-04-9 99%View Details
877179-04-9 -
2-(3,4-Dichlorophenyl)-4-FluoroanilineView Details
877179-04-9 -
5-Bromo-3-Methyl-2-Pyridinecarboxylic acid 886365-43-1 99%View Details
886365-43-1 -
186593-42-0 99%View Details
186593-42-0 -
2-Amino-4-Methylpyridine 99%View Details
695-34-1 -
370104-72-6 99%View Details
370104-72-6 -
4-Aminopyridine 99%View Details
504-24-5 -
4-dimethylaminopyridine ?1122-58-3 99%View Details
?1122-58-3
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.