2-[2-(2-methoxyethoxy)ethoxy]ethylamine
- CAS NO.：74654-07-2
- Empirical Formula: C7H17NO3
- Molecular Weight: 163.21
- MDL number: MFCD17215909
- EINECS: 277-952-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
![2-[2-(2-methoxyethoxy)ethoxy]ethylamine Structural](https://img.chemicalbook.in/CAS/GIF/74654-07-2.gif)
What is 2-[2-(2-methoxyethoxy)ethoxy]ethylamine?
Description
m-PEG3-amine is a PEG reagent containing an amino group (NH2). The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.
The Uses of 2-[2-(2-methoxyethoxy)ethoxy]ethylamine
m-PEG3-amine whose chemical name 2-[2-(2-methoxyethoxy)ethoxy]ethylamine,it is a PROTAC bridge, belonging to the PEG class, which can be used to synthesize a series of PROTAC molecules, and can also be used for the synthesis of antibody drug conjugates (ADCs).
Synthesis
2-[2-(2-methoxyethoxy)ethoxy]ethylamine is an organic intermediate, which can be prepared from triethylene glycol monomethyl ether as raw material to prepare 2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate, and then Reaction with sodium azide,and then Reacts with sodium azide to finally yield 3,6,9-trioxa-1-aminodecane.
Properties of 2-[2-(2-methoxyethoxy)ethoxy]ethylamine
| Boiling point: | 106℃ (11 Torr) |
| Density | 0.978±0.06 g/cm3(Predicted) |
| refractive index | 1.4395 (589.3 nm 20℃) |
| storage temp. | 2-8°C |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| pka | 8.74±0.10(Predicted) |
| color | Colorless to light yellow |
Safety information for 2-[2-(2-methoxyethoxy)ethoxy]ethylamine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
Computed Descriptors for 2-[2-(2-methoxyethoxy)ethoxy]ethylamine
New Products
2-(2-Chlorophenyl)glycine Propiolic Acid 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-Pentadecanol 2,4-Dihydroxybenzaldehyde Dipropyl disulfide Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Obidoxime hydrochloride API 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
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