1,8-Naphthalenediol
Synonym(s):1,8-Naphthalenediol
- CAS NO.：569-42-6
- Empirical Formula: C10H8O2
- Molecular Weight: 160.17
- MDL number: MFCD00042701
- EINECS: 209-316-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:16
What is 1,8-Naphthalenediol?
Chemical properties
1,8-Naphthalenediol [569-42-6], mp 144℃, is produced by caustic fusion of naphthosultone or naphthosultam, and by acid desulfonation of 1,8-dihydroxynaphthalene-4-sulfonic acid. It is oxidized to juglone by chromium(VI) oxide; gives a dark green color with iron(III) chloride; undergoes amination at 300℃ to give 1,8-naphthalenediamine; and couples with diazotized anilines in the 4- position.
The Uses of 1,8-Naphthalenediol
1,8-Dihydroxynaphthalene (DHN) can be used as:
- An intermediate in the preparation of benzo analogs of spiromamakone A.
- A starting material to synthesize naphthopyran derivatives.
- An intermediate in the total synthesis of palmarumycin CP17 analogs.
Definition
ChEBI: Naphthalene-1,8-diol is a member of the class of naphthalenediols that is naphthalene in which the hydrogens at positions 1 and 8 are replaced by hydroxy groups. It has a role as a fungal metabolite.
Properties of 1,8-Naphthalenediol
| Melting point: | 137-143 °C |
| Boiling point: | 140 °C(Press: 10 Torr) |
| Density | 1.33 |
| storage temp. | 2-8°C |
| pka | 6.36±0.10(Predicted) |
| BRN | 2044947 |
| CAS DataBase Reference | 569-42-6(CAS DataBase Reference) |
Safety information for 1,8-Naphthalenediol
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1,8-Naphthalenediol
New Products
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