1,8-Diaminooctane
Synonym(s):1,8-Diaminooctane;1,8-Octanediamine;Octamethylenediamine;Octamethylenediamine, 1.8-Octanediamine
- CAS NO.：373-44-4
- Empirical Formula: C8H20N2
- Molecular Weight: 144.26
- MDL number: MFCD00008248
- EINECS: 206-764-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:16:20
What is 1,8-Diaminooctane?
Chemical properties
white to yellowish solidified crystalline mass
The Uses of 1,8-Diaminooctane
1,8-Diaminooctane is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.
Definition
ChEBI: 1,8-diaminooctane is an alkane-alpha,omega-diamine in which the two amino groups are separated by eight methylene groups. It derives from a hydride of an octane.
Flammability and Explosibility
Non flammable
Safety Profile
Moderately toxic by ingestion. Asevere skin and eye irritant. When heated todecomposition it emits toxic vapors of NOx.
Purification Methods
Distil the diamine under vacuum in an inert atmosphere (N2 or Ar), cool and store the distillate in an inert atmosphere in the dark. The dihydrochloride has m 273-274o. [Nae & Le Helv Chim Acta 15 55 1955, Beilstein 4 III 612.]
Properties of 1,8-Diaminooctane
| Melting point: | 50-52 °C(lit.) |
| Boiling point: | 225-226 °C(lit.) |
| Density | 0.98 g/mL at 20 °C |
| vapor pressure | <0.1 hPa (20 °C) |
| refractive index | 1.4618 (estimate) |
| Flash point: | 329 °F |
| storage temp. | Store below +30°C. |
| solubility | 575g/l |
| form | Solidified Crystalline Mass |
| pka | 11.00, 10.1(at 20℃) |
| color | White to yellow |
| PH | 11.7 (4g/l, H2O, 20℃) |
| explosive limit | 1.1-6.8%(V) |
| Water Solubility | 575 g/L (20 ºC) |
| Sensitive | Hygroscopic |
| BRN | 1735426 |
| CAS DataBase Reference | 373-44-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,8-Diaminooctane(373-44-4) |
| EPA Substance Registry System | 1,8-Octanediamine (373-44-4) |
Safety information for 1,8-Diaminooctane
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1,8-Diaminooctane
| InChIKey | PWGJDPKCLMLPJW-UHFFFAOYSA-N |
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