16,17-Epoxypregnenolone
Synonym(s):3β-Hydroxy-16α,17α-epoxy-5-pregnen-20-one
- CAS NO.:974-23-2
- Empirical Formula: C21H30O3
- Molecular Weight: 330.47
- MDL number: MFCD00135147
- EINECS: 213-548-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-17 10:44:43
What is 16,17-Epoxypregnenolone?
Chemical properties
A crystalline compound.
The Uses of 16,17-Epoxypregnenolone
Used as intermediates of cortisone acetate, hydrocortisone, progesterone caproate, etc.
Preparation
16α,17α-Epoxypregnenolone can be prepared by oxidation, hydrolysis, elimination and epoxidation of diosgenin.
Definition
ChEBI: 3beta-hydroxy-16alpha,17alpha-epoxypregnenolone is an epoxy steroid that is pregnenolone which has an epoxy group whose oxygen is attached to the 16alpha and 17alpha-positions. It is a sterol, a 20-oxo steroid, a 3beta-hydroxy-Delta(5)-steroid, a C21-steroid and an epoxy steroid.
Properties of 16,17-Epoxypregnenolone
| Melting point: | 185-188 °C |
| Boiling point: | 462.3±45.0 °C(Predicted) |
| Density | 1.18±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 14.99±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| CAS DataBase Reference | 974-23-2(CAS DataBase Reference) |
Safety information for 16,17-Epoxypregnenolone
Computed Descriptors for 16,17-Epoxypregnenolone
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