1,4-DIOXANE-D8
Synonym(s):p-Dioxane-d8;Octadeuterodioxane
- CAS NO.:17647-74-4
- Empirical Formula: C4D8O2
- Molecular Weight: 96.15
- MDL number: MFCD00044239
- EINECS: 241-628-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:25:02
What is 1,4-DIOXANE-D8?
Chemical properties
clear colorless liquid
The Uses of 1,4-DIOXANE-D8
1,4-Dioxane-d{8} is used as a solvent in nuclear magnetic resonance (NMR) spectroscopy and acts as a stabilizer for 1,1,1-trichloroethane.
What are the applications of Application
1,4-Dioxane-d8 is a useful deuterated dioxane often used as a solvent and stabalizer for 1,1,1-trichloroethane
General Description
1,4-Dioxane-d8 is a deuterated derivative of 1,4-dioxane. It has an isotopic purity of 99atom%D. It is a standard purity solvent suitable for routine NMR analyses (conducted at ambient temperatures where quality is less critical). It is widely employed as a deuterated standard. It participates as a surrogate standard during the activated carbon SPE (solid-phase extraction) and GC-MS-SIM (gas chromatography-mass spectrometry (GC-MS) in selected ion monitoring (SIM) mode) quantification of 1,4-dioxane in drinking water.
Properties of 1,4-DIOXANE-D8
| Melting point: | 12°C |
| Boiling point: | 99 °C(lit.) |
| Density | 1.129 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 54 °F |
| storage temp. | Flammables area |
| form | Liquid |
| Specific Gravity | 1.13 |
| Water Solubility | Miscible with water. |
| Sensitive | Hygroscopic |
| BRN | 1307286 |
| CAS DataBase Reference | 17647-74-4(CAS DataBase Reference) |
| EPA Substance Registry System | 1,4-Dioxane-d8 (17647-74-4) |
Safety information for 1,4-DIOXANE-D8
| Signal word | Danger |
| Pictogram(s) |
![]() Flame Flammables GHS02 ![]() Exclamation Mark Irritant GHS07 ![]() Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H351:Carcinogenicity |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 1,4-DIOXANE-D8
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