1,4-BIS(TRIMETHYLSILYL)-1,3-BUTADIYNE

Synonym(s):1,4-Bis(trimethylsilyl)-1,3-butadiyne;BTMSBD

CAS NO.：4526-07-2
Empirical Formula: C10H18Si2
Molecular Weight: 194.42
MDL number: MFCD00009839
EINECS: 629-258-8
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-27 23:40:45

1,4-BIS(TRIMETHYLSILYL)-1,3-BUTADIYNE Structural

What is 1,4-BIS(TRIMETHYLSILYL)-1,3-BUTADIYNE?

Chemical properties

light yellow to light beige cryst.powder or flakes

The Uses of 1,4-BIS(TRIMETHYLSILYL)-1,3-BUTADIYNE

1,4-Bis(trimethylsilyl)-1,3-butadiyne is used in Negishi protocol for the synthesis of glycosylated oligo(ethynylene)s. It is also used as pharmaceutical intermediates.

The Uses of 1,4-BIS(TRIMETHYLSILYL)-1,3-BUTADIYNE

1,4-Bis(trimethylsilyl)butadiyne can be used as a reagent to prepare:

1,1,3,4-Tetrasilyl-substituted 1,3-butadienes or 1,1,3,4-tetrasilyl-substituted 1,2-butadienes by hydrosilylation reaction using various hydridosilanes and catalysts.
Glycosylated oligo(ethynylene)s using the Negishi reaction.
(±) Falcarinol, a polyacetylene class of fatty alcohol.

Properties of 1,4-BIS(TRIMETHYLSILYL)-1,3-BUTADIYNE

Melting point:	111-113 °C(lit.)
Boiling point:	197.7±23.0 °C(Predicted)
Density	0.974 g/mL at 20 °C(lit.)
refractive index	n20/D 1.384(lit.)
Flash point:	>45°C
storage temp.	2-8°C
form	solid
color	White to Light yellow to Light orange
Water Solubility	Insoluble in water.
Hydrolytic Sensitivity	4: no reaction with water under neutral conditions
BRN	1758268
CAS DataBase Reference	4526-07-2(CAS DataBase Reference)

Safety information for 1,4-BIS(TRIMETHYLSILYL)-1,3-BUTADIYNE

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02
GHS Hazard Statements	H228:Flammable solids
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.