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HomeProduct name list1,2-Octanediol

1,2-Octanediol

  • CAS NO.:1117-86-8
  • Empirical Formula: C8H18O2
  • Molecular Weight: 146.23
  • MDL number: MFCD00010738
  • EINECS: 214-254-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2025-09-01 08:52:44
1,2-Octanediol Structural

What is 1,2-Octanediol?

Chemical properties

colorless to white low melting solid
1,2-Octanediol

The Uses of 1,2-Octanediol

caprylyl glycol (1,2-Octanediol) is an emollient with moisturizing properties that may also be used as a cosmetic stabilizer. When found in combination with phenoxyethanol these two ingredients work together as an anti-microbial.

The Uses of 1,2-Octanediol

1,2-Octanediol is a novel surfactant used in the treatment of head louse. Also used in the cosmetics industry in the formulations of sunscreen gels and eye make-up.

What are the applications of Application

1,2-Octanediol is a compound used in preparation of halohydrin palmitates

Definition

ChEBI: Octane-1,2-diol is an octanediol.

Production Methods

1,2-octanediol could be obtained by epoxidation of 1-olefin with performic acid, a reaction product of hydrogen peroxide and formic acid, hydroxylation with water, or transesterification of ester produced by side reaction with methanol.

General Description

1,2-Octanediol is a potential pediculicide and is useful for treating head louse infestation clinically.

Purification Methods

Distil the diol in vacuo and/or recrystallise it from pet ether. The -naphthylurethane has m 112-114o. [Beilstein 1 III 2217, 1 IV 2590.] S-(-)-Octane-1,2-diol [87720-91-0] also crystallises from pet ether with m 35-37o and [] D -4.7o (c 35, EtOH) [Sp.th et al. Chem Ber 66 598 1933]; R-(+)-octane-1,2-diol [87720-90-9] has similar properties but with a positive optical rotation.

Properties of 1,2-Octanediol

Melting point: 36-38 °C (lit.)
Boiling point: 131-132 °C/10 mmHg (lit.)
Density  0.914
vapor density  >1 (vs air)
vapor pressure  0.28Pa at 25℃
refractive index  1.4505 (estimate)
Flash point: >230 °F
storage temp.  Sealed in dry,Room Temperature
solubility  3 g/L (20°C)
form  Low Melting Solid
pka 14.60±0.10(Predicted)
color  Colorless to white
Water Solubility  3 g/L (20 ºC)
BRN  1719619
CAS DataBase Reference 1117-86-8(CAS DataBase Reference)
NIST Chemistry Reference 1,2-Octanediol(1117-86-8)
EPA Substance Registry System 1,2-Octanediol (1117-86-8)

Safety information for 1,2-Octanediol

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H319:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for 1,2-Octanediol

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