1,2-Dihydroxynaphthalene
Synonym(s):1,2-Naphthalenediol
- CAS NO.：574-00-5
- Empirical Formula: C10H8O2
- Molecular Weight: 160.17
- MDL number: MFCD00003959
- EINECS: 209-365-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:53:06
What is 1,2-Dihydroxynaphthalene?
Chemical properties
1,2-Naphthalenediol [574-00-5], mp 108℃, is prepared by reduction of 1,2- naphthoquinone with hydrazine hydrate or sodium dithionite. It is oxidized under mild conditions to 1,2-naphthoquinone and couples with diazotized anilines in the 4-position.
The Uses of 1,2-Dihydroxynaphthalene
1,2-Dihydroxynaphthalene was used as substrate to investigate the rate of oxygen consumption by washed cell suspensions of Corynebacterium sp. strain C125 grown on o-xylene, tetralin or succinate.
Definition
ChEBI: Naphthalene-1,2-diol is a naphthalenediol. It has a role as a mouse metabolite.
General Description
1,2-Dihydroxynaphthalene is the most sensitive biomarker for an internal exposure to naphthalene in humans.
Properties of 1,2-Dihydroxynaphthalene
| Melting point: | 101-103 °C (lit.) |
| Boiling point: | 246.06°C (rough estimate) |
| Density | 1.0924 (rough estimate) |
| refractive index | 1.5178 (estimate) |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 8.42±0.50(Predicted) |
| color | Dark Brown |
| CAS DataBase Reference | 574-00-5(CAS DataBase Reference) |
Safety information for 1,2-Dihydroxynaphthalene
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1,2-Dihydroxynaphthalene
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