1,1-DIMETHOXYCYCLOHEXANE
Synonym(s):1,1-Dimethoxycyclohexane
- CAS NO.：933-40-4
- Empirical Formula: C8H16O2
- Molecular Weight: 144.21
- MDL number: MFCD00043714
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-16 09:55:36
What is 1,1-DIMETHOXYCYCLOHEXANE?
The Uses of 1,1-DIMETHOXYCYCLOHEXANE
1,1-Dimethoxycyclohexane is a useful research chemical used in the preparation of N-??substituted valiolamine derivatives as potential oral antidiabetic agents.
Synthesis Reference(s)
Canadian Journal of Chemistry, 61, p. 366, 1983 DOI: 10.1139/v83-065
Tetrahedron Letters, 30, p. 6151, 1989 DOI: 10.1016/S0040-4039(01)93328-3
General Description
Cyclohexanone dimethyl ketal reacts with trimethylsilane in the presence of trimethylsilyl triflate to form the corresponding ether. It can also undergo allylation and propargylation in the presence of indium to form the corresponding homoallylic or homopropargylic alcohol, respectively.
Properties of 1,1-DIMETHOXYCYCLOHEXANE
| Boiling point: | 83 °C/50 mmHg (lit.) |
| Density | 0.948 g/mL at 25 °C (lit.) |
| refractive index | n20/D 1.439(lit.) |
| Flash point: | 50°C |
| solubility | Chloroform (Soluble), Ethyl Acetate (Slightly) |
| form | clear liquid |
| color | Colorless to Yellow |
| CAS DataBase Reference | 933-40-4(CAS DataBase Reference) |
Safety information for 1,1-DIMETHOXYCYCLOHEXANE
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02 |
| GHS Hazard Statements |
H226:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. |
Computed Descriptors for 1,1-DIMETHOXYCYCLOHEXANE
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