1,1-Cyclopropanedicarboxylic acid
- CAS NO.：598-10-7
- Empirical Formula: C5H6O4
- Molecular Weight: 130.1
- MDL number: MFCD00013727
- EINECS: 209-917-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:55
What is 1,1-Cyclopropanedicarboxylic acid?
Chemical properties
white to almost white crystalline powder
The Uses of 1,1-Cyclopropanedicarboxylic acid
1,1-Cyclopropanedicarboxylic acid is used to prepare spiro-cyclopropyl metallocycles.1
The Uses of 1,1-Cyclopropanedicarboxylic acid
1,1-Cyclopropanedicarboxylic acid, is used as an inhibitor of 1-aminocyclopropane-1-carboxylic acid oxidase, was quantitated in Lycopersicum esculentum by HPLC-electrospray tandem mass spectrometry. Crystal and molecular structure of cyclopropane-1,1-dicarboxylic acid has been reported. Cyclopropane-1,1-dicarboxylic acid was used in the preparation of new heterocyclic derivatives of cyclopropane dicarboxylic acid containing thiadiazole and 1,2,4-triazole moieties. It was also used to prepare spiro-cyclopropyl metallocycles. It can also be used as a building block for the synthesis of a series of cyclopropanecarboxamides, having antifungal activity.
General Description
Cyclopropane-1,1-dicarboxylic acid is a dicarboxylic acid. Cyclopropane-1,1-dicarboxylic acid, an inhibitor of 1-aminocyclopropane-1-carboxylic acid oxidase, was quantitated in Lycopersicum esculentum by HPLC-electrospray tandem mass spectrometry. Crystal and molecular structure of cyclopropane-1,1-dicarboxylic acid has been reported.
Purification Methods
Recrystallise the di-acid from CHCl3, EtOAc or *C6H6/Et2O/pet ether. It forms a monohydrate. [Nicolet & Satler J Am Chem Soc 49 2070 1927, Beilstein 9 II 512, 9 III 3795.]
Properties of 1,1-Cyclopropanedicarboxylic acid
| Melting point: | 134-136 °C(lit.) |
| Boiling point: | 200.75°C (rough estimate) |
| Density | 1.3985 (rough estimate) |
| refractive index | 1.5800 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | methanol: soluble1g/10 mL, clear, colorless |
| form | powder to crystal |
| pka | 1.82(at 25℃) |
| color | White to Almost white |
| Water Solubility | Soluble |
| BRN | 1864823 |
| InChI | InChI=1S/C5H6O4/c6-3(7)5(1-2-5)4(8)9/h1-2H2,(H,6,7)(H,8,9) |
| CAS DataBase Reference | 598-10-7(CAS DataBase Reference) |
Safety information for 1,1-Cyclopropanedicarboxylic acid
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1,1-Cyclopropanedicarboxylic acid
| InChIKey | FDKLLWKMYAMLIF-UHFFFAOYSA-N |
| SMILES | C1(C(O)=O)(C(O)=O)CC1 |
1,1-Cyclopropanedicarboxylic acid manufacturer
NSR Amino Organics
SAMSON BIOSCIENCES
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