10-formyldihydrofolate
- CAS NO.：28459-40-7
- Empirical Formula: C20H21N7O7
- Molecular Weight: 471.43
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 17:18:44
What is 10-formyldihydrofolate?
The Uses of 10-formyldihydrofolate
10-Formyl-7,8-dihydrofolic acid is a novel folate found in methotrexate-treated cells. 10-Formyldihydrofolate (H2folate) has not been found as a component of intracellular folates in normal tissues but has been identified in the cytosol of methotrexate (MTX)-treated MCF-7 breast cancer cells and normal human myeloid precursor cells.
Definition
ChEBI: 10-formyldihydrofolic acid is the 10-formyl derivative of dihydrofolic acid. It is a conjugate acid of a 10-formyldihydrofolate(2-).
Properties of 10-formyldihydrofolate
| Density | 1.67±0.1 g/cm3(Predicted) |
| solubility | Aqueous Acid (Slightly), Aqueous Base (Slightly) |
| pka | 3.38±0.10(Predicted) |
| form | Solid |
| color | Orange to Very Dark Brown |
| Stability: | Hygroscopic, Temperature Sensitive |
Safety information for 10-formyldihydrofolate
Computed Descriptors for 10-formyldihydrofolate
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