1-Isopropyl-1H-pyrazole-5-boronic acid, pinacol ester
- CAS NO.：1282518-60-8
- Empirical Formula: C12H21BN2O2
- Molecular Weight: 236.12
- MDL number: MFCD17167306
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 00:05:19
What is 1-Isopropyl-1H-pyrazole-5-boronic acid, pinacol ester?
Synthesis
1-Isopropyl-1H-pyrazole-5-boronic acid, pinacol ester could be synthesized through the reaction of 1-isopropyl-1H-pyrazole with 2-isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane. Tetrahydrofuran could used as an organic solvent. The crude product added n-hexane, heated to 40°C to dissolve the system, cooled to -20°C, stirred and crystallized, and filtered. Vacuum drying to obtain the target compound 1-Isopropyl-1H-pyrazole-5-boronic acid, pinacol ester, with a yield of 77% and a purity of 99.3%.
Properties of 1-Isopropyl-1H-pyrazole-5-boronic acid, pinacol ester
| Boiling point: | 327.3±15.0 °C(Predicted) |
| Density | 1.03±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| pka | 1.98±0.10(Predicted) |
| form | solid |
| color | White to off-white |
Safety information for 1-Isopropyl-1H-pyrazole-5-boronic acid, pinacol ester
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. |
Computed Descriptors for 1-Isopropyl-1H-pyrazole-5-boronic acid, pinacol ester
New Products
2-Bromo-4-hydroxypyridine Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Cis-Tosylate 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 1-aminocyclobutanecarbonitrile hydrochloride AMINO-O-TOLYL-ACETIC ACID 1-Aminocyclobutanecarboxylic Acid Hydrochloride AMINO(2-BROMOPHENYL)ACETIC ACID 6-BROMOTETRAZOLO[1,5-A]PYRIDINE 3-Oxocyclobutanecarboxylic acid METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 2-(2-Bromophenyl)ethanol Boc-D-Glu(OMe)-OMe 2,5 Dibromopyridine Ethyl 4-hydroxy-3-oxobutanoate Dimethyl (2S)-2-((tert-butoxycarbonyl)amino)-4-(cyanomethyl)pentanedioate 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
![2-(3-BroMo-2-fluoro-phenyl)-4,4,5,5-tetraMethyl-[1,3,2]dioxaborolane](https://img.chemicalbook.in/CAS/20150408/GIF/1400220-51-0.gif)
![2-(4-BroMo-2,6-difluoro-phenyl)-4,4,5,5-tetraMethyl-[1,3,2]dioxaborolane](https://img.chemicalbook.in/CAS/20150408/GIF/CB52656859.gif)
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