1-HEXADECYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
Synonym(s):1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine
- CAS NO.：95403-34-2
- Empirical Formula: C42H84NO7P
- Molecular Weight: 746.11
- MDL number: MFCD11974148
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 02:46:56
What is 1-HEXADECYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE?
The Uses of 1-HEXADECYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
C16-18:1 PC or 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine may be used in the liposome binding assay. It may also be used as a lipid standard for quantification of glycerophosphocholine by liquid chromatography–mass spectrometry (LC–MS).
The Uses of 1-HEXADECYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
C16-18:1 PC or 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine may be used: as a lipid standard for quantification of glycerophosphocholine by liquid chromatography–mass spectrometry (LC–MS), in preparation of phospholipid vesicles, as a substrate to study the substrate specificity of phospholipase B/lipase (PLB/LIP) in the presence and absence of deoxycholate (DOC).
Definition
ChEBI: 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine (O-16:0/18:1) in which the alkyl and the acyl groups at positions 1 and 2 are hexadecyl and oleoyl respectively. It is functionally related to an oleic acid and a lysophosphatidylcholine O-16:0/0:0.
General Description
C16-18:1 PC, also called as 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine (HOPC), is a member of platelet-activating factor (PAF) family of glycerophospholipids. HOPC is a mono-ether PC containing ester-linked 18:1 chain (oleoyl) at the sn-2 position and an ether-linked 16:0 chain (hexadecyl) at the sn-1 position.
Biochem/physiol Actions
Platelet-activating factor (PAF), a lipid mediator acts as a pro-inflammatory agent that exhibits variety of biological and pharmacological effects.
Properties of 1-HEXADECYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
| storage temp. | -20°C |
Safety information for 1-HEXADECYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity H372:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 1-HEXADECYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
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